DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12605 and ZBTB14

DIOPT Version :9

Sequence 1:NP_001261387.1 Gene:CG12605 / 38468 FlyBaseID:FBgn0035481 Length:619 Species:Drosophila melanogaster
Sequence 2:NP_001137295.1 Gene:ZBTB14 / 7541 HGNCID:12860 Length:449 Species:Homo sapiens


Alignment Length:318 Identity:78/318 - (24%)
Similarity:120/318 - (37%) Gaps:93/318 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   332 DVDIDMSSSSESGL--------QQWGKPNPQQNQQRASALKMCLNMLDGRTKASKAAAVTKQDRQ 388
            ||::.|||....|:        |:....:|.:|..::.: |.||.:    .:....||.|:.|..
Human   104 DVNLMMSSGQILGIRFLDKLCSQKRDVSSPDENNGQSKS-KYCLKI----NRPIGDAADTQDDDV 163

  Fly   389 EPMQPRPKSAQSNASSGGGPPSEPPENPAASLGHSSS-----GNGENYAKRKRGCY--------- 439
            |.:..:..|...:...|..|..|..::|..:|....:     |:.|   .||..||         
Human   164 EEIGDQDDSPSDDTVEGTPPSQEDGKSPTTTLRVQEAILKELGSEE---VRKVNCYGQEVESMET 225

  Fly   440 ----------------------------------------------------KCCECGKQYATSS 452
                                                                .|..|||.::...
Human   226 PESKDLGSQTPQALTFNDGMSEVKDEQTPGWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEG 290

  Fly   453 NLSRHKQTHRSLDSQSAKK---CNTCGKAYVSMPALAMHLLTHK--LSHSCDICGKLFSRPWLLQ 512
            .|.:|::.|      :|.:   |..|.|.:.:...|..||..|.  ..:||::|||.|.|...|:
Human   291 RLRKHEKLH------TADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLK 349

  Fly   513 GHLRSHTGEKPYACVHCGKAFADRSNLRAHMQTHSGDKNFKCHRCNKTFALKSYLNKH 570
            .|.|.|:.|:|:||..|.|||..:|:|:.|.:.|.|:|.|.|..|.|.||..|.|.:|
Human   350 KHERVHSNERPFACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRH 407

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12605NP_001261387.1 zf-C2H2 439..461 CDD:278523 7/82 (9%)
C2H2 Zn finger 441..461 CDD:275370 6/19 (32%)
C2H2 Zn finger 472..492 CDD:275368 6/19 (32%)
COG5048 492..>570 CDD:227381 34/79 (43%)
zf-C2H2 496..518 CDD:278523 10/21 (48%)
C2H2 Zn finger 498..518 CDD:275368 9/19 (47%)
zf-H2C2_2 511..534 CDD:290200 11/22 (50%)
zf-C2H2 524..546 CDD:278523 9/21 (43%)
C2H2 Zn finger 526..546 CDD:275368 8/19 (42%)
zf-H2C2_2 538..562 CDD:290200 9/23 (39%)
C2H2 Zn finger 554..571 CDD:275368 8/17 (47%)
ZBTB14NP_001137295.1 BTB_POZ_ZBTB14 18..131 CDD:349513 7/26 (27%)
Nuclear localization signal. /evidence=ECO:0000255 50..66
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 153..194 10/40 (25%)
C2H2 Zn finger 279..299 CDD:275368 6/19 (32%)
SFP1 <303..383 CDD:227516 29/79 (37%)
C2H2 Zn finger 307..327 CDD:275368 6/19 (32%)
zf-H2C2_2 319..344 CDD:404364 10/24 (42%)
C2H2 Zn finger 335..355 CDD:275368 9/19 (47%)
C2H2 Zn finger 363..383 CDD:275368 8/19 (42%)
C2H2 Zn finger 391..407 CDD:275368 7/15 (47%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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