DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12605 and CG7691

DIOPT Version :9

Sequence 1:	NP_001261387.1	Gene:	CG12605 / 38468	FlyBaseID:	FBgn0035481	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	NP_650728.1	Gene:	CG7691 / 42228	FlyBaseID:	FBgn0038626	Length:	283	Species:	Drosophila melanogaster

Alignment Length:	303	Identity:	77/303 - (25%)
Similarity:	116/303 - (38%)	Gaps:	69/303 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   299 RFIGSSS--YDLMGGSSEGANNCSPLTPPNSDHSSDVDIDMSSSSESGLQQWGKPNPQQNQQRAS 361
            |:.|...  ||......:...|..|:..|.::|.|.|..              ||.|:.|.:
  Fly    12 RYNGKQERFYDRYEDFCQVIPNLPPMPRPKTNHHSRVAT--------------KPEPKTNVK--- 59

  Fly   362 ALKMCLNMLDGRTKAS-------KAAAVTKQDRQEPMQPRPKSAQSNASSGGGPPSEPPENPAAS 419
             ...|.    |:::.|       ....|.:::.:|.:             |....|..|...::.
  Fly    60 -FTYCF----GQSEPSGDWRQGDDIPIVVRREMEERL-------------GIQLMSVLPITESSL 106

  Fly   420 LGHS---SSGNGENY---AKRKRGCYKCCECGKQYATSSNLSRHKQTHRSLDSQSAKKCN-TCGK 477
            |.|:   ....||::   .|.:.|    .:.|....|:.:    |||...|..:.....| |...
  Fly   107 LSHTIWELKMPGESFDSIPKTRNG----IKVGIITVTAES----KQTRTKLKRKGPILANVTVPS 163

  Fly   478 AYVSMPALAMHLLTHKL-------SHSCDICGKLFSRPWLLQGHLRSHTGEKPYACV--HCGKAF 533
            ..|.:|.:....:..|.       ...|..|.|.|...|:|..|.|:||||||:.|.  .|.|||
  Fly   164 NIVEIPPIQQRKMPEKRRLKRVGGQFECIDCDKKFDHSWMLTAHTRTHTGEKPFVCPDGSCRKAF 228

  Fly   534 ADRSNLRAHMQTHSGDK-NFKCHRCNKTFALKSYLNKHLESAC 575
            :||||||:|.:|....: ..:|.:|.|.|:..||||:|...||
  Fly   229 SDRSNLRSHQRTMGHHEWQHQCGQCGKYFSQFSYLNRHSLDAC 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12605	NP_001261387.1	zf-C2H2	439..461	CDD:278523	4/21 (19%)
		C2H2 Zn finger	441..461	CDD:275370	4/19 (21%)
		C2H2 Zn finger	472..492	CDD:275368	4/20 (20%)
		COG5048	492..>570	CDD:227381	36/87 (41%)
		zf-C2H2	496..518	CDD:278523	8/21 (38%)
		C2H2 Zn finger	498..518	CDD:275368	8/19 (42%)
		zf-H2C2_2	511..534	CDD:290200	13/24 (54%)
		zf-C2H2	524..546	CDD:278523	12/23 (52%)
		C2H2 Zn finger	526..546	CDD:275368	12/21 (57%)
		zf-H2C2_2	538..562	CDD:290200	8/24 (33%)
		C2H2 Zn finger	554..571	CDD:275368	8/16 (50%)
CG7691	NP_650728.1	COG5048	188..>271	CDD:227381	36/82 (44%)
		C2H2 Zn finger	191..211	CDD:275368	8/19 (42%)
		zf-H2C2_2	203..229	CDD:290200	13/25 (52%)
		C2H2 Zn finger	219..244	CDD:275368	13/24 (54%)
		C2H2 Zn finger	250..266	CDD:275368	8/15 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2462
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810