DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12605 and CG15446

DIOPT Version :9

Sequence 1:	NP_001261387.1	Gene:	CG12605 / 38468	FlyBaseID:	FBgn0035481	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	NP_608430.2	Gene:	CG15446 / 33088	FlyBaseID:	FBgn0031155	Length:	373	Species:	Drosophila melanogaster

Alignment Length:	375	Identity:	70/375 - (18%)
Similarity:	134/375 - (35%)	Gaps:	80/375 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   243 EETEAAHDLLSLSQSLPPLIPPCVVTIMKQEQEQLRSPEIQEISNSASSRSPQSTIRFIGSSSYD 307
            |..|||       :.:.|.:|.|        |..:...|::. .|:..:|.|.|..:....|...
  Fly    18 ERYEAA-------RIIHPSLPEC--------QRPVEPTEVKH-PNNPVNRRPVSYRQMANQSRRQ 66

  Fly   308 LMGGS--------------SEGANNCSPLTPPNSDHSSDVDIDMSSSSESGLQQWGKPNPQQNQQ 358
            |...|              .|..|....::..|::.::.|      .|.:|..:.|:|     ..
  Fly    67 LENDSWLSSDRLPMMVRHEIETRNKKQLMSKYNAETATHV------FSHNGGPRRGRP-----PS 120

  Fly   359 RASALKMC---LNMLDGRTKASKAAAVTKQDRQEPMQPRPKSAQ-------SNASSGGGPPSE-- 411
            .|:|.:|.   ...:.|.:::.......|...|..|||:.|.|.       ...::...|.||
  Fly   121 AATAARMASEFARQVGGISQSPTIEDEGKSGEQSVMQPKSKKANKMPDKVADKLATKSEPKSEES 185

  Fly   412 --PPENPAASLGHSSSGN-GENYAKRKRGCYKCCECGKQYATSSN----LSRHKQTHRSLDSQSA 469
              |.:.....:.|::.|: .::.....:|          :.|:.|    ||.....:|::|....
  Fly   186 NVPVKIKVEGVEHNAEGSQSDSMVNTNQG----------FTTNRNFIPILSSFPNPYRNMDVTWT 240

  Fly   470 KKCNTCGKAYVS--MPALAMHLLTHKLSHSCDICGKLFSRPWLLQGHLRSHTGEKPYACV--HCG 530
            ::.|.....|.:  |.:::.......|:.:......:|....::.|.   |.....::|.  :|.
  Fly   241 EQFNALSNQYYNHIMNSISSLSQIQPLNSTPSANPPIFGANPMVMGR---HPPFSVFSCPLDYCK 302

  Fly   531 KAFADRSNLRAHMQTHSGDKNF--KCHRCNKTFALKSYLNKHLESACLRD 578
            :.|..|..:..| |..:|..|:  .|.:|.:.|....::..|..:||.|:
  Fly   303 ENFDSRRAMYKH-QRETGHHNWPHNCSKCGQVFRTSGFMRMHSVNACARN 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12605	NP_001261387.1	zf-C2H2	439..461	CDD:278523	4/25 (16%)
		C2H2 Zn finger	441..461	CDD:275370	4/23 (17%)
		C2H2 Zn finger	472..492	CDD:275368	3/21 (14%)
		COG5048	492..>570	CDD:227381	15/81 (19%)
		zf-C2H2	496..518	CDD:278523	2/21 (10%)
		C2H2 Zn finger	498..518	CDD:275368	2/19 (11%)
		zf-H2C2_2	511..534	CDD:290200	4/24 (17%)
		zf-C2H2	524..546	CDD:278523	6/23 (26%)
		C2H2 Zn finger	526..546	CDD:275368	6/21 (29%)
		zf-H2C2_2	538..562	CDD:290200	6/25 (24%)
		C2H2 Zn finger	554..571	CDD:275368	3/16 (19%)
CG15446	NP_608430.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2462
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810