DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12605 and CG10959

DIOPT Version :10

Sequence 1:NP_647845.2 Gene:CG12605 / 38468 FlyBaseID:FBgn0035481 Length:619 Species:Drosophila melanogaster
Sequence 2:NP_572451.1 Gene:CG10959 / 31743 FlyBaseID:FBgn0030010 Length:443 Species:Drosophila melanogaster


Alignment Length:385 Identity:90/385 - (23%)
Similarity:141/385 - (36%) Gaps:98/385 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   265 CVVTIMKQEQEQLRSPEIQEISNSASSRSPQSTIRFIG---SSSYDLMGGSSEGANNCSPLTP-- 324
            |::..||....:..:..|:.:......|....|:..:|   ....:..|.|:|      ||..  
  Fly    40 CLLCDMKHFGFEDFARHIRNVHFDKQGRPLTKTVTGLGRLAREEQEFQGVSAE------PLAVDS 98

  Fly   325 ------PNSDHSSDVDIDMSSSSESGLQQWGKPNPQQNQQRASALKMCLNMLDGRTKASKAAAVT 383
                  ||.|..|:   :..:..|.||:| .:.||           :.:.:|.|:....:....|
  Fly    99 FKKEYLPNEDVLSE---EEDAEQELGLEQ-DEGNP-----------LRIMVLGGKQSVDEETIDT 148

  Fly   384 KQDRQEPMQPRPKSAQSNASSGGGPPSEP---PENPAASLGHSSSGNGENY-----AKRKRGCYK 440
            ..        :|....|:||...|...|.   .|||.   .:....:||.:     .:|:...|.
  Fly   149 MW--------QPDHDSSSASVNEGCALEALLGVENPQ---DYQPDEDGEEHQSVFKKQRQPKDYN 202

  Fly   441 CCECGKQYATSSNLSRH-KQTHRSLDSQSAKKCNTCGKAYVSMPALAMHLLTHKLSHSCDICGKL 504
            |..|.::|.|...|:.| |.:|   ....|.||..|...:....|||.|........:|.:|.|:
  Fly   203 CPHCDRRYTTQKYLNTHLKMSH---PFPQAFKCVDCKATFDVDRALAQHRRKEHTEFACQLCDKV 264

  Fly   505 FSRPWLLQGHLRSHTGEKPYACVH--CGKAFADRSNLRA-------------------------- 541
            |.....|..|::.|:|.:.:.|.|  |||:|.::.||.:                          
  Fly   265 FKSSRSLLRHVQGHSGARTFKCEHENCGKSFVNQHNLTSHRRVHSEERNYVCELCGYRSRYREAL 329

  Fly   542 --HMQTHSGDKNFKCHRCNKTFALKSYLNKHLESACLRDAGAIDQGKGLEEEDDDCSKQD 599
              |.:||:|:|.|:|..|.:.||.||.||:|             |.....|:...|.|.|
  Fly   330 IVHRRTHTGEKPFQCQTCARRFASKSLLNEH-------------QAMHSTEKPYKCDKCD 376

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12605NP_647845.2 COG5048 283..>561 CDD:227381 74/327 (23%)
zf-C2H2 439..461 CDD:395048 8/22 (36%)
C2H2 Zn finger 441..461 CDD:275370 7/20 (35%)
C2H2 Zn finger 472..492 CDD:275368 6/19 (32%)
zf-C2H2 496..518 CDD:395048 6/21 (29%)
C2H2 Zn finger 498..518 CDD:275368 6/19 (32%)
zf-H2C2_2 511..534 CDD:463886 9/24 (38%)
zf-C2H2 524..546 CDD:395048 9/51 (18%)
C2H2 Zn finger 526..546 CDD:275368 9/49 (18%)
zf-H2C2_2 538..562 CDD:463886 10/51 (20%)
C2H2 Zn finger 554..571 CDD:275368 8/16 (50%)
CG10959NP_572451.1 C2H2 Zn finger 232..253 CDD:275368 6/20 (30%)
COG5048 <258..416 CDD:227381 36/132 (27%)
C2H2 Zn finger 258..278 CDD:275368 6/19 (32%)
C2H2 Zn finger 289..308 CDD:275368 6/18 (33%)
C2H2 Zn finger 316..336 CDD:275368 1/19 (5%)
C2H2 Zn finger 344..364 CDD:275368 10/32 (31%)
C2H2 Zn finger 372..392 CDD:275368 3/5 (60%)
C2H2 Zn finger 400..420 CDD:275368
Blue background indicates that the domain is not in the aligned region.

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