DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12605 and Zbtb46

DIOPT Version :9

Sequence 1:NP_001261387.1 Gene:CG12605 / 38468 FlyBaseID:FBgn0035481 Length:619 Species:Drosophila melanogaster
Sequence 2:NP_001101278.1 Gene:Zbtb46 / 311718 RGDID:1307408 Length:601 Species:Rattus norvegicus


Alignment Length:509 Identity:101/509 - (19%)
Similarity:163/509 - (32%) Gaps:169/509 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   222 MREQQLVAATAAASIYRGRSVEETEAAHDLLSLSQSLPPLIPPCVVTIMKQEQEQLRSPEIQEIS 286
            :..:.::...:|||..:...:  .:|.||.:..:..         ::|.....::|...||    
  Rat    97 LTSRNVIEVMSAASFLQMTDI--VQACHDFIKAALD---------ISIKSDASDELSEFEI---- 146

  Fly   287 NSASSRSPQSTIRFI----------------GSSSYDLM------GGSSEGANNCSPLTPPNSDH 329
            .:.:|.|.::.|..:                .:||.|..      ||||.|..:..|......|.
  Rat   147 GTPASNSTEALISAVMAGRSISPWLARRTSPANSSGDSAIASCHEGGSSYGKEDQEPKADGPDDV 211

  Fly   330 SS------DVDI------------------DMSSSSESGLQQ----------WGKPNPQQNQQRA 360
            ||      ||..                  ::|||.::.:|.          |.....::|::..
  Rat   212 SSQSLWPGDVGYGSLRIKEEQISPSHYGGSELSSSKDAAIQNSLSEQGSGDGWQPTGRRKNRKNK 276

  Fly   361 SALKMCLNMLDGRTKASKAAAVTKQDRQEPMQPRPKSAQ---SNASS------------------ 404
            ..::.....::..::|.............|...|..:..   :.|||                  
  Rat   277 ETVRHITQQVEEDSQAGSPVPSFLPTSGWPFSSRDSNVDLTVTEASSLDSRGERAELYAHHIDEG 341

  Fly   405 --GG-----GPPSEPPENPAASLGHSSSGNGENYAKRKRGCYKCCECGKQYATSSNLSRHKQTHR 462
              ||     |||..|.:..|.                           .|....:||.....:..
  Rat   342 LLGGETSYLGPPLTPEKEEAL---------------------------HQATAVANLRAALMSKN 379

  Fly   463 SLDSQSAKKCNTCGK-AYVSMPALAMHLLTHKLS----------HSCDICGKLFSRPWLLQGHLR 516
            ||.|..|......|. .:..:|..|     |.||          ..|..|........:|:.|:|
  Rat   380 SLLSLKADVLGDDGSLLFEYLPKGA-----HSLSLNEFTVIRKKFKCPYCSFSAMHQCILKRHMR 439

  Fly   517 SHTGEKPYACVHCGKAFADRSNLRAHMQTHSGDKNFKCHRCNKTF------ALKSYLNKHLESAC 575
            |||||:||.|..|||.|..|.:::.|...||.||.:.|..|::.|      .:|....:|  ..|
  Rat   440 SHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAASVGIKHGSRRH--GVC 502

  Fly   576 LRDAG-----AIDQGKGLE--------------EEDDDCSKQDELEMGDELESD 610
            ...||     .:|.|.|.|              |:.||...:.|.|:|::.:.|
  Rat   503 ADCAGRGVGTPLDHGGGGEGSPEALFAGEGPYLEDPDDPRGEVEEELGEDEDED 556

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12605NP_001261387.1 zf-C2H2 439..461 CDD:278523 3/21 (14%)
C2H2 Zn finger 441..461 CDD:275370 3/19 (16%)
C2H2 Zn finger 472..492 CDD:275368 3/20 (15%)
COG5048 492..>570 CDD:227381 30/93 (32%)
zf-C2H2 496..518 CDD:278523 5/21 (24%)
C2H2 Zn finger 498..518 CDD:275368 5/19 (26%)
zf-H2C2_2 511..534 CDD:290200 14/22 (64%)
zf-C2H2 524..546 CDD:278523 8/21 (38%)
C2H2 Zn finger 526..546 CDD:275368 7/19 (37%)
zf-H2C2_2 538..562 CDD:290200 8/29 (28%)
C2H2 Zn finger 554..571 CDD:275368 4/22 (18%)
Zbtb46NP_001101278.1 BTB 21..126 CDD:279045 6/30 (20%)
BTB 32..126 CDD:197585 6/30 (20%)
COG5048 <362..>487 CDD:227381 39/156 (25%)
C2H2 Zn finger 421..441 CDD:275368 5/19 (26%)
zf-H2C2_2 434..458 CDD:290200 15/23 (65%)
C2H2 Zn finger 449..469 CDD:275368 7/19 (37%)
zf-H2C2_2 461..484 CDD:290200 7/22 (32%)
C2H2 Zn finger 477..499 CDD:275368 4/21 (19%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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