DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12605 and Zfp641

DIOPT Version :9

Sequence 1:	NP_001261387.1	Gene:	CG12605 / 38468	FlyBaseID:	FBgn0035481	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	NP_001100262.1	Gene:	Zfp641 / 300197	RGDID:	1310412	Length:	421	Species:	Rattus norvegicus

Alignment Length:	275	Identity:	81/275 - (29%)
Similarity:	115/275 - (41%)	Gaps:	52/275 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   335 IDMSSSSESGLQQWGKPNPQQNQQRASALKMCLNMLDGRTKASKAAAVTKQDR------QEPMQP 393
            :||....|.|.:|| .|:||..:.| ...|:......|..|.......|:..|      :|.:..
  Rat   142 LDMLPQLEGGEEQW-VPDPQDVEGR-DIRKVTYAGDGGEPKGDTPELETEPSRTLSSMSEETVLW 204

  Fly   394 RP---KSAQSNASSGGGPPSEPPENPAASLGH-SSSGNGENYAKRKRGCYKCCECGKQYATSSNL 454
            .|   .|.:|..||..|....|......|:.| ..|.:.::..|.    :.|.:||||:...|:|
  Rat   205 NPGQGPSWRSMPSSSTGTLPRPRFLQEDSVSHLLRSTDTDSLLKP----HTCPQCGKQFVWGSHL 265

  Fly   455 SRHKQTHRSLDSQSAKKC-NTCGKAYVSMPALAMHLLTHKLSH------SCDICGKLFSRPWLLQ 512
            :||:|||......|..|| .:.|:.:        ||:.|:.:|      .|..|||.|.....|.
  Rat   266 ARHQQTHTGERPYSCLKCEKSFGRRH--------HLIRHQKTHLHDKPSRCPECGKTFRCSSHLA 322

  Fly   513 GHLRSHT----------GEKP-----------YACVHCGKAFADRSNLRAHMQTHSGDKNFKCHR 556
            .|.|.|.          ||.|           :.|..|||:|..|.:|..|..||:|:|.|.|.|
  Rat   323 SHQRVHADSKSCKGQEIGESPGAQCAPPVPKCHVCTECGKSFGRRHHLVRHWLTHTGEKPFHCPR 387

  Fly   557 CNKTFALKSYLNKHL 571
            |.|:|..|.:|::||
  Rat   388 CEKSFGRKHHLDRHL 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12605	NP_001261387.1	zf-C2H2	439..461	CDD:278523	10/21 (48%)
		C2H2 Zn finger	441..461	CDD:275370	10/19 (53%)
		C2H2 Zn finger	472..492	CDD:275368	4/20 (20%)
		COG5048	492..>570	CDD:227381	34/104 (33%)
		zf-C2H2	496..518	CDD:278523	9/27 (33%)
		C2H2 Zn finger	498..518	CDD:275368	8/19 (42%)
		zf-H2C2_2	511..534	CDD:290200	11/43 (26%)
		zf-C2H2	524..546	CDD:278523	8/21 (38%)
		C2H2 Zn finger	526..546	CDD:275368	8/19 (42%)
		zf-H2C2_2	538..562	CDD:290200	11/23 (48%)
		C2H2 Zn finger	554..571	CDD:275368	7/16 (44%)
Zfp641	NP_001100262.1	PLN03206	<13..90	CDD:178745
		KRAB	95..156	CDD:214630	6/14 (43%)
		COG5048	<208..402	CDD:227381	62/205 (30%)
		C2H2 Zn finger	252..272	CDD:275368	10/19 (53%)
		C2H2 Zn finger	280..300	CDD:275368	6/27 (22%)
		C2H2 Zn finger	308..328	CDD:275368	8/19 (42%)
		C2H2 Zn finger	357..377	CDD:275368	8/19 (42%)
		C2H2 Zn finger	385..405	CDD:275368	9/18 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	111	1.000	Inparanoid score	I4772
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050