DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12605 and Zbtb16

DIOPT Version :9

Sequence 1:NP_001261387.1 Gene:CG12605 / 38468 FlyBaseID:FBgn0035481 Length:619 Species:Drosophila melanogaster
Sequence 2:NP_001028496.1 Gene:Zbtb16 / 235320 MGIID:103222 Length:673 Species:Mus musculus


Alignment Length:630 Identity:140/630 - (22%)
Similarity:214/630 - (33%) Gaps:216/630 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    55 RTSGKVKFDDKSPLTASSVLKNANGNGLGTGGKSPLKSLAKRNSRSILKREIIDL---------- 109
            |.|.....|..||.|...:|:.|.        .:.|::.|:.....:...||:::          
Mouse    65 RNSQHYTLDFLSPKTFQQILEYAY--------TATLQAKAEDLDDLLYAAEILEIEYLEEQCLKI 121

  Fly   110 -------DDED---------GEEQEDQLCEHLEWSAAQSLVQMNSSKQE---------------K 143
                   ||.|         |||:||:...:|:    ...:..:||::.               .
Mouse   122 LETIQASDDNDTEATMADGGGEEEEDRKARYLK----NIFISKHSSEESGYASVAGQSLPGPMVD 182

  Fly   144 QRRAGTTGSPATVAAPVSASVSLRRPVGRAPAEDGKVIFYAPPA-----SASGSPRQPEPVALKR 203
            |..:.:|....:..:|..|:|.....:|::..: |.:   .|||     :.:|..|.|....:|.
Mouse   183 QSPSVSTSFGLSAMSPTKAAVDSLMSIGQSLLQ-GTL---QPPAGPEEPTLAGGGRHPGVAEVKM 243

  Fly   204 ERER----------------------DKEREREKERERDRMREQQLVAATAAASIYRGRSVEETE 246
            |..:                      ||..||.||......|...:   |:|..::.||      
Mouse   244 EMMQVDEAPGQDSPGAAESSISGGMGDKLEERSKEGPGTPTRGSVI---TSARELHYGR------ 299

  Fly   247 AAHDLLSLSQSLPPLIPPCVVTIMKQEQEQLRSPEIQEISNSASSRSPQSTIRFIGSSSYDLMGG 311
                                    ::..||| ||.::      :.:.|.               |
Mouse   300 ------------------------EESGEQL-SPPVE------AGQGPP---------------G 318

  Fly   312 SSEGANNCSPLTPPNS----------DHSSDVDIDMSSSSESGLQQWGKPNPQQNQQRASALKMC 366
            ..|      ||.||..          :|.:|..:.|.||..|||          :.|.|.|:.|.
Mouse   319 RQE------PLAPPVEKHLGIYSVLPNHKADAVLSMPSSVTSGL----------HVQPALAVSMD 367

  Fly   367 LNMLDG--------RTKASKAAAVTKQDRQEPMQPRPKSAQSNASSGGGPPSEPPENPAASLGHS 423
            .:...|        |...||...:....:.|   .||...|.:...     .|.|:|.|......
Mouse   368 FSTYGGLLPQGFIQRELFSKLGELAVGMKAE---SRPLGEQCSVCG-----VELPDNEAVEQHRK 424

  Fly   424 SSGNGENYAKRKRGC--------------------------YKCCECGKQYATSSNLSRHKQTHR 462
            .....:.|     ||                          :.|.:||.|::....|..|:|||.
Mouse   425 LHSGMKTY-----GCELCGKRFLDSLRLRMHLLAHSAGAKAFVCDQCGAQFSKEDALETHRQTHT 484

  Fly   463 SLDSQSAKKCNTCGKAYVSMPALAMHLLTHK--LSHSCDICGKLFSRPWLLQGHLRSHTGEKPYA 525
            ..|  .|..|..|||.:.:..||..|:..|.  .|:.|..|.:.|.....|:.|||||||:.||.
Mouse   485 GTD--MAVFCLLCGKRFQAQSALQQHMEVHAGVRSYICSECNRTFPSHTALKRHLRSHTGDHPYE 547

  Fly   526 CVHCGKAFADRSNLRAHMQTHSGDKNFKCHRCNKTFALKSYLNKH 570
            |..||..|.|.|.|::|.:.|:|:|.::|:.|.|.|:||..|..|
Mouse   548 CEFCGSCFRDESTLKSHKRIHTGEKPYECNGCGKKFSLKHQLETH 592

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12605NP_001261387.1 zf-C2H2 439..461 CDD:278523 7/21 (33%)
C2H2 Zn finger 441..461 CDD:275370 7/19 (37%)
C2H2 Zn finger 472..492 CDD:275368 7/19 (37%)
COG5048 492..>570 CDD:227381 33/79 (42%)
zf-C2H2 496..518 CDD:278523 7/21 (33%)
C2H2 Zn finger 498..518 CDD:275368 7/19 (37%)
zf-H2C2_2 511..534 CDD:290200 13/22 (59%)
zf-C2H2 524..546 CDD:278523 9/21 (43%)
C2H2 Zn finger 526..546 CDD:275368 8/19 (42%)
zf-H2C2_2 538..562 CDD:290200 8/23 (35%)
C2H2 Zn finger 554..571 CDD:275368 8/17 (47%)
Zbtb16NP_001028496.1 BTB_POZ_ZBTB16_PLZF 16..122 CDD:349514 12/64 (19%)
C2H2 Zn finger 406..426 CDD:275368 4/24 (17%)
C2H2 Zn finger 434..454 CDD:275368 1/19 (5%)
COG5048 <448..622 CDD:227381 52/147 (35%)
C2H2 Zn finger 463..483 CDD:275368 7/19 (37%)
C2H2 Zn finger 492..512 CDD:275368 7/19 (37%)
C2H2 Zn finger 520..540 CDD:275368 7/19 (37%)
C2H2 Zn finger 548..568 CDD:275368 8/19 (42%)
C2H2 Zn finger 576..596 CDD:275368 8/17 (47%)
C2H2 Zn finger 604..624 CDD:275368
C2H2 Zn finger 632..652 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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