Protein Alignment CG12605 and klu-1

DIOPT Version :10

• Sequence 1: NP_647845.2
• Gene: CG12605 / 38468
• FlyBaseID: FBgn0035481
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_493611.2
• Gene: klu-1 / 173366
• WormBaseID: WBGene00013970
• Length: 543
• Species: Caenorhabditis elegans
• Alignment Length: 377
• Identity: 83/377 - (22%)
• Similarity: 138/377 - (36%)
• Gaps: 114/377 - (30%)

  Fly   226 QLVAATAAASIYRGRSVEETEAAHDLLSLSQSLPPLIPPCVVTIMKQEQEQLRSPEIQEISNSAS 290
            ||:||.||..:.|.||..|::                       |:..||.    :::.::.|..
 Worm   173 QLLAAGAAYELSRERSRSESD-----------------------MQPTQED----DVRHLNTSTI 210

  Fly   291 SRSPQSTIRFIGSSSYDLMGGSSEGANNCSPLTPPNSDHSSDVDIDMSSSSESGLQ--------- 346
            |      :...........||.   ....|...||.||....|:..:.....||::
 Worm   211 S------VPIYAKKPLHKFGGE---IKRSSSTPPPTSDEREQVEQRLLLRPSSGMEIKKDLETTN 266

  Fly   347 ----QWGKPNPQQNQQRASALKMCLNMLDGRTKASKAAAVTKQDRQEPMQ--PRPKSAQSNASSG 405
                .|.:     .|..|.......|:|..|: |...:.::...   |::  ||.|...:.|..
 Worm   267 SFVSSWAR-----EQIFAMQNATMYNLLTARS-AEDCSTISTPG---PLKVFPRSKDDMTFAPR- 321

  Fly   406 GGPPSEPPENPAASLGHSSSGNGENYAKRKRGCYKCCECGKQYATSSNL-----SRHKQTHRSLD 465
                                   ::.::.|:..|.|..||:.:|....|     |||:|...:||
 Worm   322 -----------------------DDSSRAKQMQYPCTLCGQAFAVHDRLAKHIASRHRQRSCTLD 363

  Fly   466 SQSAKKCNTCGKAYVSMPALAMHLLTHKLSHSCDICGKLFSRPWLLQGHLRSHTGEKPYACVHCG 530
            ..|.                         .|.|::|.|.|||..:|..|:|.|||.|||:|..|.
 Worm   364 DASK-------------------------VHKCNMCSKSFSRSDMLTRHMRLHTGAKPYSCPTCN 403

  Fly   531 KAFADRSNLRAHMQTHSGDKNFKCHRCNKTFALKSYLNKHLESACLRDAGAI 582
            :.|:...:|..|::||:|:|.:.|..||.:.:.:..:::|:.:..|.|..:|
 Worm   404 QVFSRSDHLSTHLRTHTGEKPYACPMCNYSASRRDMISRHMRTHSLTDDSSI 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12605	NP_647845.2	COG5048	283..>561	CDD:227381	66/297 (22%)
		zf-C2H2	439..461	CDD:395048	10/26 (38%)
		C2H2 Zn finger	441..461	CDD:275370	9/24 (38%)
		C2H2 Zn finger	472..492	CDD:275368	0/19 (0%)
		zf-C2H2	496..518	CDD:395048	10/21 (48%)
		C2H2 Zn finger	498..518	CDD:275368	9/19 (47%)
		zf-H2C2_2	511..534	CDD:463886	11/22 (50%)
		zf-C2H2	524..546	CDD:395048	6/21 (29%)
		C2H2 Zn finger	526..546	CDD:275368	5/19 (26%)
		zf-H2C2_2	538..562	CDD:463886	9/23 (39%)
		C2H2 Zn finger	554..571	CDD:275368	3/16 (19%)
klu-1	NP_493611.2	C2H2 Zn finger	334..354	CDD:275368	5/19 (26%)
		COG5048	362..>540	CDD:227381	35/119 (29%)
		zf-C2H2	369..391	CDD:395048	10/21 (48%)
		C2H2 Zn finger	371..391	CDD:275368	9/19 (47%)
		zf-C2H2	397..419	CDD:395048	6/21 (29%)
		C2H2 Zn finger	399..419	CDD:275368	5/19 (26%)
		zf-H2C2_2	411..436	CDD:463886	9/24 (38%)
		C2H2 Zn finger	427..447	CDD:275368	4/19 (21%)