DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12605 and Snai1

DIOPT Version :9

Sequence 1:	NP_001261387.1	Gene:	CG12605 / 38468	FlyBaseID:	FBgn0035481	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	NP_446257.1	Gene:	Snai1 / 116490	RGDID:	620758	Length:	264	Species:	Rattus norvegicus

Alignment Length:	194	Identity:	81/194 - (41%)
Similarity:	111/194 - (57%)	Gaps:	20/194 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   390 PMQPRPKSAQ--SNASSGGGPPSEPPENPAASLGHSSSGNGENYAKRKRGCYKCCECGKQYATSS 452
            |::..|::|:  |.:....|..|:||..|:.:....||.:..:..            .:.:....
  Rat    78 PLRESPRAAELTSLSDEDSGKSSQPPSPPSPAPSSFSSTSASSLE------------AEAFIAFP 130

  Fly   453 NLSR-HKQTHR---SLDSQSAK--KCNTCGKAYVSMPALAMHLLTHKLSHSCDICGKLFSRPWLL 511
            .|.: .||..|   :.|.||.|  .|..|.|.|:|:.||.||:.:|.|...|..|||.|||||||
  Rat   131 GLGQLPKQLARLSVAKDPQSRKAFNCKYCNKEYLSLGALKMHIRSHTLPCVCTTCGKAFSRPWLL 195

  Fly   512 QGHLRSHTGEKPYACVHCGKAFADRSNLRAHMQTHSGDKNFKCHRCNKTFALKSYLNKHLESAC 575
            |||:|:||||||::|.||.:|||||||||||:||||..|.::|..|.:||:..|.|:||.||.|
  Rat   196 QGHVRTHTGEKPFSCSHCNRAFADRSNLRAHLQTHSDVKRYQCQACARTFSRMSLLHKHQESGC 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12605	NP_001261387.1	zf-C2H2	439..461	CDD:278523	3/22 (14%)
		C2H2 Zn finger	441..461	CDD:275370	3/20 (15%)
		C2H2 Zn finger	472..492	CDD:275368	9/19 (47%)
		COG5048	492..>570	CDD:227381	48/77 (62%)
		zf-C2H2	496..518	CDD:278523	15/21 (71%)
		C2H2 Zn finger	498..518	CDD:275368	15/19 (79%)
		zf-H2C2_2	511..534	CDD:290200	15/22 (68%)
		zf-C2H2	524..546	CDD:278523	15/21 (71%)
		C2H2 Zn finger	526..546	CDD:275368	15/19 (79%)
		zf-H2C2_2	538..562	CDD:290200	13/23 (57%)
		C2H2 Zn finger	554..571	CDD:275368	7/16 (44%)
Snai1	NP_446257.1	C2H2 Zn finger	156..176	CDD:275368	9/19 (47%)
		COG5048	<177..>253	CDD:227381	47/75 (63%)
		zf-C2H2	180..202	CDD:278523	15/21 (71%)
		C2H2 Zn finger	182..202	CDD:275368	15/19 (79%)
		zf-H2C2_2	195..218	CDD:290200	15/22 (68%)
		zf-C2H2	208..230	CDD:278523	15/21 (71%)
		C2H2 Zn finger	210..230	CDD:275368	15/19 (79%)
		C2H2 Zn finger	238..255	CDD:275368	7/16 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810