DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12605 and bcl6ab

DIOPT Version :9

Sequence 1:NP_001261387.1 Gene:CG12605 / 38468 FlyBaseID:FBgn0035481 Length:619 Species:Drosophila melanogaster
Sequence 2:XP_005171194.1 Gene:bcl6ab / 100001936 ZFINID:ZDB-GENE-030131-7523 Length:566 Species:Danio rerio


Alignment Length:424 Identity:106/424 - (25%)
Similarity:146/424 - (34%) Gaps:135/424 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   168 RPVGRAPAEDGKVIFYAPPASASGSPRQPEPVALKRERERDKEREREKERERDRMREQQLVAATA 232
            |.:..|..|||                             ||||.|.....|....|....|...
Zfish   227 RTITNAAVEDG-----------------------------DKERNRPSVLFRSARAEGNRKAPLL 262

  Fly   233 AASIYRGRSVEETEAAHDLLSLSQSLPPLIPPCVVTIMKQEQEQLRSPEIQEISNSASSR---SP 294
            ::      .||..||.|    ......||...|          |..||    ..:|..||   ||
Zfish   263 SS------EVENIEACH----TGGPESPLRSDC----------QPNSP----AESSGCSRRPASP 303

  Fly   295 QSTI-----------RFIGSSSYDLMGGSSEGANNCSPLTPPNSDHSSDVDIDMSSSSESGLQQW 348
            .|:|           :||..:|.|           .|.||||::         :|.|:....:..
Zfish   304 PSSITYAKVHNWKKYKFIVLNSTD-----------NSSLTPPHT---------VSESTNQNAEHK 348

  Fly   349 GKPNPQ-----QNQQRASALKMCLNMLDGRTKASKAAAVTKQDRQ-------EPMQPRPKSAQSN 401
            |:.|..     :.::..|::....      |:.|...:....:|:       |....:|:..|. 
Zfish   349 GQDNRSTDECIKKEEHGSSVHNTF------TEESSMGSTNSAERERVYCNECESEAEKPQWLQD- 406

  Fly   402 ASSGGGPPSEPPE---------NPAASLGHSSSGNGENYAKRKRGCYKCCECGKQYATSSNLSRH 457
                 |.|.:...         ||.:|  |.|...||.       .|:|..||.|:...:||..|
Zfish   407 -----GKPYKCDRCQAMFHYKGNPLSS--HKSVHTGEK-------PYRCNVCGAQFNRPANLKTH 457

  Fly   458 KQTHRSLDSQSAKKCNTCGKAYVSMPALAMHLLTH--KLSHSCDICGKLFSRPWLLQGHLRSHTG 520
            .:.|   ..:...||.||...:|.:..|..|:|.|  :..:.|||||..|.....|:.|||.|||
Zfish   458 SRIH---SGEKPYKCETCSSRFVQVAHLRAHVLIHTGEKPYPCDICGTRFRHLQTLKSHLRIHTG 519

  Fly   521 EKPYACVHCGKAFADRSNLRAHM-QTHSGDKNFK 553
            ||||.|.:|...|..:|.||.|: |.|....|.|
Zfish   520 EKPYHCENCDLRFRHKSQLRLHLRQKHGAITNTK 553

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12605NP_001261387.1 zf-C2H2 439..461 CDD:278523 8/21 (38%)
C2H2 Zn finger 441..461 CDD:275370 7/19 (37%)
C2H2 Zn finger 472..492 CDD:275368 7/19 (37%)
COG5048 492..>570 CDD:227381 29/65 (45%)
zf-C2H2 496..518 CDD:278523 10/21 (48%)
C2H2 Zn finger 498..518 CDD:275368 10/19 (53%)
zf-H2C2_2 511..534 CDD:290200 13/22 (59%)
zf-C2H2 524..546 CDD:278523 9/22 (41%)
C2H2 Zn finger 526..546 CDD:275368 8/20 (40%)
zf-H2C2_2 538..562 CDD:290200 7/17 (41%)
C2H2 Zn finger 554..571 CDD:275368 106/424 (25%)
bcl6abXP_005171194.1 BTB 22..126 CDD:279045
BTB 33..128 CDD:197585
C2H2 Zn finger 412..433 CDD:275368 5/22 (23%)
zf-H2C2_2 426..450 CDD:290200 10/32 (31%)
C2H2 Zn finger 441..461 CDD:275368 7/19 (37%)
zf-H2C2_2 453..478 CDD:290200 8/27 (30%)
C2H2 Zn finger 469..489 CDD:275368 7/19 (37%)
zf-H2C2_2 481..506 CDD:290200 10/24 (42%)
C2H2 Zn finger 497..517 CDD:275368 10/19 (53%)
zf-H2C2_2 510..534 CDD:290200 14/23 (61%)
C2H2 Zn finger 525..543 CDD:275368 7/17 (41%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
00.000

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