DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14983 and Rnf4

DIOPT Version :9

Sequence 1:NP_647843.1 Gene:CG14983 / 38466 FlyBaseID:FBgn0035479 Length:163 Species:Drosophila melanogaster
Sequence 2:NP_001291198.1 Gene:Rnf4 / 19822 MGIID:1201691 Length:194 Species:Mus musculus


Alignment Length:59 Identity:22/59 - (37%)
Similarity:32/59 - (54%) Gaps:4/59 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly   101 CSIC-DLKCE--PHGRHSMVSLRCGHLFGRHCINNVLRESSRCPTCSRRARHHEVRRIY 156
            |.|| |...|  .:|| .:||..|||:|...|:.:.|:.::.||||.::..|.....||
Mouse   136 CPICMDGYSEIVQNGR-LIVSTECGHVFCSQCLRDSLKNANTCPTCRKKINHKRYHPIY 193

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14983NP_647843.1 zf-RING_2 99..143 CDD:290367 17/44 (39%)
Rnf4NP_001291198.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..39
Required for ubiquitination activity 1..20
Mediates interaction with TRPS1. /evidence=ECO:0000269|PubMed:12885770 6..65
SUMO interaction motif 1, mediates the binding to polysumoylated substrates. /evidence=ECO:0000250|UniProtKB:P78317 40..43
SUMO interaction motif 2, mediates the binding to polysumoylated substrates. /evidence=ECO:0000250|UniProtKB:P78317 50..53
SUMO interaction motif 3, mediates the binding to polysumoylated substrates. /evidence=ECO:0000250|UniProtKB:P78317 61..63
SUMO interaction motif 4, mediates the binding to polysumoylated substrates. /evidence=ECO:0000250|UniProtKB:P78317 71..74
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 110..130
zf-RING_2 135..181 CDD:290367 18/45 (40%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0001208
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.910

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