DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14983 and Rfwd3

DIOPT Version :9

Sequence 1:	NP_647843.1	Gene:	CG14983 / 38466	FlyBaseID:	FBgn0035479	Length:	163	Species:	Drosophila melanogaster
Sequence 2:	XP_341691.8	Gene:	Rfwd3 / 103690025	RGDID:	1305243	Length:	765	Species:	Rattus norvegicus

Alignment Length:	146	Identity:	31/146 - (21%)
Similarity:	62/146 - (42%)	Gaps:	33/146 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 KELQEQEKEIQEIILEESFASPEQRLAQLESVTSRMHLYHSRRGNILMSLQQELGKYEYFTLLVR 76
            :|...:.:|.:..:.|:...|.:|..|.:....:.......::..:|.:::.|.|:
  Rat   222 EEAAARAEEPEAAVPEQGVISTDQEAASVTGGDASPKKQSPQKPIVLPTVEDEEGE--------- 277

  Fly    77 HIAQTHSYLKSLNKALDFLYKVNICSICDLKCEPHGRHSMVSLRCGHLFGRHCINNVLR-ESSRC 140
                                   .|:||..:....|.|.:.:||||||||..||...|: ::.:|
  Rat   278 -----------------------TCTICLEQWTSAGDHRLSALRCGHLFGYRCIFKWLKGQTRKC 319

  Fly   141 PTCSRRARHHEVRRIY 156
            |.|:::|:|.::..:|
  Rat   320 PQCNKKAKHSDIVVLY 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14983	NP_647843.1	zf-RING_2	99..143	CDD:290367	18/44 (41%)
Rfwd3	XP_341691.8	mRING-C3HGC3_RFWD3	275..323	CDD:319364	19/79 (24%)
		WD40	<470..>624	CDD:225201
		WD40 repeat	491..528	CDD:293791
		WD40 repeat	534..572	CDD:293791
		WD40 repeat	579..617	CDD:293791
		WD40 repeat	692..731	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1451258at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010