DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14982 and Fam110b

DIOPT Version :9

Sequence 1:	NP_001261385.1	Gene:	CG14982 / 38464	FlyBaseID:	FBgn0035477	Length:	773	Species:	Drosophila melanogaster
Sequence 2:	NP_001342645.1	Gene:	Fam110b / 242297	MGIID:	1916593	Length:	366	Species:	Mus musculus

Alignment Length:	390	Identity:	78/390 - (20%)
Similarity:	137/390 - (35%)	Gaps:	112/390 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   423 HYTHRSEPCYKR----ER-----------QREVAGSAAPASGTIKNCCTLVAATRRDSGSSTQHS 472
            ::..::||..||    ||           |..:.....|....:.....:...|:|..||.|
Mouse    36 YFRRQAEPNPKRLSAVERLEADKAKYVKSQEVINAKQEPVKPAVLAKPPVCPGTKRALGSPT--- 97

  Fly   473 ANSYCGYVTPAGDYSGMGGGRNTECLD-------CRCKQDTTMGSDY---LLNFTPTPEVPEAFQ 527
                   :...|:::....|...|.|.       ....:.::.||.:   ..|:.|..:..:..:
Mouse    98 -------LKVFGNHAKTESGVQRETLKLEILKNIINSSEGSSSGSGHKHSSRNWPPHRDTTDLHR 155

  Fly   528 DDYT------PTPPSPRLKTQTPRYSSS--SSQQLHTSSQGYTSINHSQSSLVQ----SPGSAPS 580
            ..:.      |||..     .:|:.|||  |.:.|..|::.:..::||.|.:.:    .|..|..
Mouse   156 HSFAESLKVYPTPGH-----GSPQESSSHVSRRLLEQSAETFLHVSHSSSDIRKVTSVKPLKAIP 215

  Fly   581 VDDISPPPIQFKRQRCIRFKNRNRLPVQGEMGGPPGSGGGLVAPGSGGMGTASGVLAAYKQHRGS 645
            ....:||                 ||       |......:.:|.:..:..|.||.......|..
Mouse   216 CSSSAPP-----------------LP-------PKPKVAAMKSPEADQVEPACGVSRRPSLQRSK 256

  Fly   646 VDHENVFFPKGFSSEVYHNSLDMEREALNASISELEKFFDRLGLNDEAFHEIYSQP-RRHHSETD 709
            .|..:.:|           .:|          :::|:||:..||:.|....:..:. .|.:|:..
Mouse   257 SDLSDRYF-----------RVD----------ADVERFFNYCGLDPEELENLGMENFARANSDII 300

  Fly   710 DASDDSSTVFFSDV-STVDS---MRLPDSTETQ-PQATQAYRPSEPPSIVERNARIIKWLCNCKK 769
            ..:..|:::..||. .:.||   :|..||...: |....|         :||||||||||.:.|:
Mouse   301 SLNFRSASMISSDCEQSQDSNSDLRNDDSANDRVPYGISA---------IERNARIIKWLYSIKQ 356

Fly 770 769
Mouse 357 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14982	NP_001261385.1	FAM110_C	663..770	CDD:290865	30/113 (27%)
Fam110b	NP_001342645.1	FAM110_N	17..118	CDD:372938	17/91 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	127..152		4/24 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	163..182		7/23 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	216..252		9/59 (15%)
		FAM110_C	249..357	CDD:372937	33/138 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	313..333		6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28WFT
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D326385at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14758
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010