Protein Alignment CG10863 and GCY1

DIOPT Version :9

• Sequence 1: NP_647840.1
• Gene: CG10863 / 38463
• FlyBaseID: FBgn0027552
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_014763.1
• Gene: GCY1 / 854287
• SGDID: S000005646
• Length: 312
• Species: Saccharomyces cerevisiae
• Alignment Length: 310
• Identity: 127/310 - (40%)
• Similarity: 175/310 - (56%)
• Gaps: 29/310 - (9%)

  Fly     2 SSKIPYVKHNNGTQIQSIGLGTYTSLGGDCERATLHAIDVGYRHIDTAYFYENENEVGAAVQRKI 66
            |:||  :..|.|.||..|||||:.|...|..:|.|.|:..||||||||..|.||::||.|::
Yeast     8 STKI--LSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIK--- 67

  Fly    67 AEGVIKREDIHITTKLWC-HFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPY----SYVYRGDNE 126
             :..:.||:|.:|||||| ..|||   |.|..::|:..||.||||||||||.    :|:...|..
Yeast    68 -DSGVPREEIFVTTKLWCTQHHEP---EVALDQSLKRLGLDYVDLYLMHWPARLDPAYIKNEDIL 128

  Fly   127 MMPT--DAKGEVELNDIDYLDTWREMEKLVELGLTKSIGVSNFNSEQLTRLLAN--CKIKPIHNQ 187
            .:||  |....|::.:.:::.||..|::|.:.|.||::|||||:...|..|||:  .|:.|..||
Yeast   129 SVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTPAANQ 193

  Fly   188 IECHPALNQKKLIALCKKNDIVVTAYCPLGRPN-PAEKTPNYIYDAKVQAIGDKYKKSTAQVVLR 251
            :|.||.|.|.:||..||...|||.||.|||..: |..|.|..:..||      |.......||:.
Yeast   194 VEIHPLLPQDELINFCKSKGIVVEAYSPLGSTDAPLLKEPVILEIAK------KNNVQPGHVVIS 252

  Fly   252 YLIEIGTIPLPKSSNPKRIEENFQIFDFQLDAEDHAILD--SYNTGERLI 299
            :.::.|.:.||||.||.||:.|.:|  |.|..||...::  |...||:.:
Yeast   253 WHVQRGYVVLPKSVNPDRIKTNRKI--FTLSTEDFEAINNISKEKGEKRV 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10863	NP_647840.1	ARA1	6..304	CDD:223729	124/306 (41%)
		Tas	11..290	CDD:223739	121/288 (42%)
GCY1	NP_014763.1	AKR_AKR3A1-2	7..296	CDD:381343	125/304 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345942
Domainoid	1	1.000	202	1.000	Domainoid score	I552
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	209	1.000	Inparanoid score	I815
Isobase	1	0.950	-	0	Normalized mean entropy	S875
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	1	1.000	-	-		otm46528
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
TreeFam	0	0.000	Not matched by this tool.
	10	9.640