Protein Alignment CG10863 and AKR1E2

DIOPT Version :9

• Sequence 1: NP_647840.1
• Gene: CG10863 / 38463
• FlyBaseID: FBgn0027552
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: XP_011518017.1
• Gene: AKR1E2 / 83592
• HGNCID: 23437
• Length: 341
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 137/317 - (43%)
• Similarity: 177/317 - (55%)
• Gaps: 42/317 - (13%)

  Fly    29 GDCERATLHAIDVGYRHIDTAYFYENENEVGAAVQRKIAEGVIKREDIHITTKLWCHFHEPKRVE 93
            |....|...|||.||||.|.||||.||.||||.::.||.||.::|||:.|.|||||..|:...||
Human    38 GKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVE 102

  Fly    94 YACRKTLQNFGLQYVDLYLMHWPYSYV------YRGDNEM-----------MPTDAKGEVELNDI 141
            .||||:|:...|.|:||||:|||..:.      ....:|:           :|.|....|..:|.
Human   103 TACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIPSDT 167

  Fly   142 DYLDTWREMEKLVELGLTKSIGVSNFNSEQLTRLL--ANCKIKPIHNQIECHPALNQKKLIALCK 204
            |:||||..||.||..||.|:|||||||.|||.|||  ...:.||:.|||||||.|.||.||:.|:
Human   168 DFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQ 232

  Fly   205 KNDIVVTAYCPLGR--------PNPAEKTPNYIYDAKVQAIGDKYKKSTAQVVLRYLIEIGTIPL 261
            ..|:.||||.|||.        .||.           ::.|..::.||.||:::|:.|:...|.:
Human   233 SRDVSVTAYRPLGGSCEGVDLIDNPV-----------IKRIAKEHGKSPAQILIRFQIQRNVIVI 286

  Fly   262 PKSSNPKRIEENFQIFDFQLDAEDHAILDSYNTGERL--IPMTHAIKSKNYPFNIEF 316
            |.|..|..|:||.|:|||:|...|...:.|.|...||  .|:|.  ..|:|||:||:
Human   287 PGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPITK--NHKDYPFHIEY 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10863	NP_647840.1	ARA1	6..304	CDD:223729	131/303 (43%)
		Tas	11..290	CDD:223739	125/287 (44%)
AKR1E2	XP_011518017.1	ARA1	34..322	CDD:223729	127/294 (43%)
		Tas	42..314	CDD:223739	124/282 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.730