DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10863 and AKR4C8

DIOPT Version :9

Sequence 1:	NP_647840.1	Gene:	CG10863 / 38463	FlyBaseID:	FBgn0027552	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_565871.1	Gene:	AKR4C8 / 818353	AraportID:	AT2G37760	Length:	311	Species:	Arabidopsis thaliana

Alignment Length:	281	Identity:	111/281 - (39%)
Similarity:	165/281 - (58%)	Gaps:	11/281 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSSKIPYVKHNNGTQIQSIGLGTYTSLGGDCERATLHAIDVGYRHIDTAYFYENENEVGAAVQRK 65
            |::.|.:.:.|.|.::..:|||||..:....|:    ||.:||||||.|..|.||.|:|..:::.
plant     1 MAAPIRFFELNTGAKLPCVGLGTYAMVATAIEQ----AIKIGYRHIDCASIYGNEKEIGGVLKKL 61

  Fly    66 IAEGVIKREDIHITTKLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPYSYVYRGDNEMMPT 130
            |.:|.:|||::.||:|||.:.|.|:.|..|..||||:..:.||||||:|||.|.   ....:|||
plant    62 IGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASL---KKESLMPT 123

  Fly   131 DAKGEVELNDIDYLDTWREMEKLVELGLTKSIGVSNFNSEQLTRLLANCKIKPIHNQIECHPALN 195
            ...    |...|...||:.||.|.:.|..::||||||:|::||.||...::.|..||:||||...
plant   124 PEM----LTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPVWQ 184

  Fly   196 QKKLIALCKKNDIVVTAYCPLGRPNPAEKTPNYIYDAKVQAIGDKYKKSTAQVVLRYLIEIGTIP 260
            |:.|..|||...:.::.|.|||..:..|.....:.:..|..:.:|..|:||||.||:.::.|...
plant   185 QQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIVTEVAEKLGKTTAQVALRWGLQTGHSV 249

  Fly   261 LPKSSNPKRIEENFQIFDFQL 281
            |||||:..|::||..:||:.:
plant   250 LPKSSSGARLKENLDVFDWSI 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10863	NP_647840.1	ARA1	6..304	CDD:223729	109/276 (39%)
CG10863	NP_647840.1	Tas	11..290	CDD:223739	109/271 (40%)
AKR4C8	NP_565871.1	AKR_AKR4C1-15	6..288	CDD:381351	109/276 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	244	1.000	Domainoid score	I557
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	248	1.000	Inparanoid score	I1036
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	1	1.000	-	-		otm2923
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.780