Protein Alignment CG10863 and akr1c3

DIOPT Version :10

• Sequence 1: NP_647840.1
• Gene: CG10863 / 38463
• FlyBaseID: FBgn0027552
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_001072181.1
• Gene: akr1c3 / 779627
• XenbaseID: XB-GENE-5821909
• Length: 324
• Species: Xenopus tropicalis
• Alignment Length: 325
• Identity: 136/325 - (41%)
• Similarity: 189/325 - (58%)
• Gaps: 17/325 - (5%)

  Fly     4 KIPYVKHNNGTQIQSIGLGTYT------SLGGDCERATLHAIDVGYRHIDTAYFYENENEVGAAV 62
            |..||:.|:|.::..||.|||.      ||   .|..|..||||||||||.|:.|.||.|||.|:
 Frog     5 KDSYVELNDGHKMPVIGFGTYAPPKFPKSL---AEEGTKVAIDVGYRHIDCAFLYGNEEEVGRAI 66

  Fly    63 QRKIAEGVIKREDIHITTKLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPYSYVYRGDNEM 127
            :.|||:|.:||||:..|.|||...|.|:||..|..|:|::..|.|:||:::|.|..  ::..:::
 Frog    67 RAKIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPME--FKPGDDL 129

  Fly   128 MPTDAKGEVELNDIDYLDTWREMEKLVELGLTKSIGVSNFNSEQLTRLL--ANCKIKPIHNQIEC 190
            .|.|..|:...::.|..|||:.:||..:.||.:||||||||.:||..:|  ...|.||:.||:||
 Frog   130 FPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPGLKYKPVCNQVEC 194

  Fly   191 HPALNQKKLIALCKKNDIVVTAYCPLGRPNPAE----KTPNYIYDAKVQAIGDKYKKSTAQVVLR 251
            |..|||.||:..||..|||:..|..||......    .||..:.|..:..|..|:.::.|||.:|
 Frog   195 HVYLNQSKLLEFCKSKDIVLVGYSVLGSSRDERWIEASTPVLLEDPALTEIAKKHNRTPAQVAMR 259

  Fly   252 YLIEIGTIPLPKSSNPKRIEENFQIFDFQLDAEDHAILDSYNTGERLIPMTHAIKSKNYPFNIEF 316
            |.::.|.:.|.||..|.||::|||:|||||||||...:|..|...|.|..:.......||::.|:
 Frog   260 YHLQRGVVVLAKSFTPARIQQNFQVFDFQLDAEDMRSIDGLNRNMRYIDTSRWSDHPKYPYSEEY 324

  Fly   317  316
             Frog   325  324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10863	NP_647840.1	AKR_AKR2E1-5	6..299	CDD:381342	131/304 (43%)
akr1c3	NP_001072181.1	AKR_AKR1C1-35	8..308	CDD:381334	131/304 (43%)