Protein Alignment CG10863 and Akr1c21

DIOPT Version :10

• Sequence 1: NP_647840.1
• Gene: CG10863 / 38463
• FlyBaseID: FBgn0027552
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_084177.2
• Gene: Akr1c21 / 77337
• MGIID: 1924587
• Length: 323
• Species: Mus musculus
• Alignment Length: 327
• Identity: 128/327 - (39%)
• Similarity: 183/327 - (55%)
• Gaps: 15/327 - (4%)

  Fly     1 MSSKIPYVKHNNGTQIQSIGLGTYTSLGGDCERA-----TLHAIDVGYRHIDTAYFYENENEVGA 60
            |:||...|..|:|..|..:|.||...|  :|.::     |..|||.|:.|.|:|..|..|:.||.
Mouse     1 MNSKCHCVILNDGNFIPVLGFGTALPL--ECPKSKAKELTKIAIDAGFHHFDSASVYNTEDHVGE 63

  Fly    61 AVQRKIAEGVIKREDIHITTKLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPYSYVYRGDN 125
            |::.|||:|.::||||..|:|:||....|:.|..:..::||.....||||||:|:|.:  .:...
Mouse    64 AIRSKIADGTVRREDIFYTSKVWCTSLHPELVRASLERSLQKLQFDYVDLYLIHYPMA--LKPGE 126

  Fly   126 EMMPTDAKGEVELNDIDYLDTWREMEKLVELGLTKSIGVSNFNSEQLTRLL--ANCKIKPIHNQI 188
            |..|.|..|::..:.:|...||..|||..:.||||||||||||..||..:|  ...|.||:.||:
Mouse   127 ENFPVDEHGKLIFDRVDLCATWEAMEKCKDAGLTKSIGVSNFNYRQLEMILNKPGLKYKPVCNQV 191

  Fly   189 ECHPALNQKKLIALCKKNDIVVTAYCPLGRPNPA----EKTPNYIYDAKVQAIGDKYKKSTAQVV 249
            ||||.|||.||:..||..|||:.||..||.....    :.:|..:.:..:.::..||.::.|.:.
Mouse   192 ECHPYLNQMKLLDFCKSKDIVLVAYGVLGTQRYGGWVDQNSPVLLDEPVLGSMAKKYNRTPALIA 256

  Fly   250 LRYLIEIGTIPLPKSSNPKRIEENFQIFDFQLDAEDHAILDSYNTGERLIPMTHAIKSKNYPFNI 314
            |||.::.|.:.|..|...:||:||.|:|:|||.:||..:||..|...|.||........|:||..
Mouse   257 LRYQLQRGIVVLNTSLKEERIKENMQVFEFQLSSEDMKVLDGLNRNMRYIPAAIFKGHPNWPFLD 321

  Fly   315 EF 316
            |:
Mouse   322 EY 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10863	NP_647840.1	AKR_AKR2E1-5	6..299	CDD:381342	119/303 (39%)
Akr1c21	NP_084177.2	AKR_AKR1C1-35	6..308	CDD:381334	120/305 (39%)