Protein Alignment CG10863 and Akr1cl

DIOPT Version :10

• Sequence 1: NP_647840.1
• Gene: CG10863 / 38463
• FlyBaseID: FBgn0027552
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_081858.2
• Gene: Akr1cl / 70861
• MGIID: 1918111
• Length: 322
• Species: Mus musculus
• Alignment Length: 321
• Identity: 135/321 - (42%)
• Similarity: 194/321 - (60%)
• Gaps: 15/321 - (4%)

  Fly     7 YVKHNNGTQIQSIGLGTYTSLGGDCE-----RATLHAIDVGYRHIDTAYFYENENEVGAAVQRKI 66
            |::.::|..|..:|.||:  :.|:..     :||..|||.|:||||:||||:||.|||.|::.|:
Mouse     6 YMELSDGHHIPVLGFGTF--VPGEVSKSMVAKATKIAIDAGFRHIDSAYFYQNEEEVGLAIRSKV 68

  Fly    67 AEGVIKREDIHITTKLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPYSYVYRGDNEMMPTD 131
            |:|.::||||..|:||.|..|.|:.|:....::|:...|.||||||:|.|.|  .:..|:::|||
Mouse    69 ADGTVRREDIFYTSKLPCTCHRPELVQPCLEQSLRKLQLDYVDLYLIHCPVS--MKPGNDLIPTD 131

  Fly   132 AKGEVELNDIDYLDTWREMEKLVELGLTKSIGVSNFNSEQLTRLL--ANCKIKPIHNQIECHPAL 194
            ..|::..:.:|..|||..|||..:.||.|||||||||..||..:|  ...:.||:.||:||||.|
Mouse   132 ENGKLLFDTVDLCDTWEAMEKCKDSGLAKSIGVSNFNRRQLEMILNKPGLRYKPVCNQVECHPYL 196

  Fly   195 NQKKLIALCKKNDIVVTAYCPLGRPN----PAEKTPNYIYDAKVQAIGDKYKKSTAQVVLRYLIE 255
            ||.||:..||..|||:.||..||...    ..|..|..:.|..:.|:.:|:|::.|.:.||||::
Mouse   197 NQSKLLDYCKSKDIVLVAYGALGSQRCKNWIEENAPYLLEDPTLCAMAEKHKQTPALISLRYLLQ 261

  Fly   256 IGTIPLPKSSNPKRIEENFQIFDFQLDAEDHAILDSYNTGERLIPMTHAIKSKNYPFNIEF 316
            .|.:.:.||.|.|||:||.::|:|.|.|||.|::|..|...|...........||||..|:
Mouse   262 RGIVIVTKSFNEKRIKENLKVFEFHLPAEDMAVIDRLNRNYRYATARIISAHPNYPFLDEY 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10863	NP_647840.1	AKR_AKR2E1-5	6..299	CDD:381342	130/302 (43%)
Akr1cl	NP_081858.2	AKR_AKR1C1-35	5..307	CDD:381334	130/304 (43%)