Protein Alignment CG10863 and Akr1b10

DIOPT Version :10

• Sequence 1: NP_647840.1
• Gene: CG10863 / 38463
• FlyBaseID: FBgn0027552
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_765986.3
• Gene: Akr1b10 / 67861
• MGIID: 1915111
• Length: 316
• Species: Mus musculus
• Alignment Length: 309
• Identity: 137/309 - (44%)
• Similarity: 191/309 - (61%)
• Gaps: 7/309 - (2%)

  Fly    13 GTQIQSIGLGTYTSLGGDCERATLHAIDVGYRHIDTAYFYENENEVGAAVQRKIAEGVIKREDIH 77
            |.::..:||||:.|.......|...|||.||||||.||.|:||:|||.|:|.||.|..:||||:.
Mouse    10 GAKMPIVGLGTWKSPPAKVREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQEKIQEKAVKREDLF 74

  Fly    78 ITTKLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPYSYVYRGDNEMMPTDAKGEVELNDID 142
            |.:|||..|.|...|:.|.:.||.:..|.|:||||:|||..  ::..|..:|||.||.:..:...
Mouse    75 IVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQG--FQSGNVFLPTDDKGSILSSKYT 137

  Fly   143 YLDTWREMEKLVELGLTKSIGVSNFNSEQLTRLL--ANCKIKPIHNQIECHPALNQKKLIALCKK 205
            :||.|..||:||:.||.|::||||||..|:.|||  ...|.||:.||:||||.|.|:|||..|..
Mouse   138 FLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHS 202

  Fly   206 NDIVVTAYCPLG---RPNPAEKTPNYIYDAKVQAIGDKYKKSTAQVVLRYLIEIGTIPLPKSSNP 267
            ..|.:|||.|||   ||:...:.|..:...|::.|..|:|::.|||::|:.||...:.:|||..|
Mouse   203 KGITITAYSPLGSPDRPSAKPEDPLLLEIPKIKEIAAKHKRTAAQVLIRFHIERNVVVIPKSVTP 267

  Fly   268 KRIEENFQIFDFQLDAEDHAILDSYNTGERLIPMTHAIKSKNYPFNIEF 316
            .||:||.|:|||||..||.|.:.|:|...|...:..|..::::||:.|:
Mouse   268 SRIQENIQVFDFQLSEEDMAAILSFNRNWRACGLFAASHNEDFPFHAEY 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10863	NP_647840.1	AKR_AKR2E1-5	6..299	CDD:381342	133/290 (46%)
Akr1b10	NP_765986.3	AKR_AKR1B1-19	10..316	CDD:381333	136/307 (44%)