Protein Alignment CG10863 and AKR1D1

DIOPT Version :9

• Sequence 1: NP_647840.1
• Gene: CG10863 / 38463
• FlyBaseID: FBgn0027552
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_005980.1
• Gene: AKR1D1 / 6718
• HGNCID: 388
• Length: 326
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 135/325 - (41%)
• Similarity: 192/325 - (59%)
• Gaps: 15/325 - (4%)

  Fly     2 SSKIPYVKHNNGTQIQSIGLGTY----TSLGGDCERATLHAIDVGYRHIDTAYFYENENEVGAAV 62
            |.:||.   ::|..|..||||||    ::..|.|..:...|||.||||||.||.|:||:|||.|:
Human     7 SHRIPL---SDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAI 68

  Fly    63 QRKIAEGVIKREDIHITTKLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPYSYVYRGDNEM 127
            :.|||||.::||||....|||...|.|:.|.....:||:...|.|||||::..|.:  ::..:|:
Human    69 REKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA--FKPGDEI 131

  Fly   128 MPTDAKGEVELNDIDYLDTWREMEKLVELGLTKSIGVSNFNSEQLTRLL--ANCKIKPIHNQIEC 190
            .|.|..|:...:..:...||..||...:.||.||:||||||..||..:|  ...|.||:.||:||
Human   132 YPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVEC 196

  Fly   191 HPALNQKKLIALCKKNDIVVTAYCPLGRP-NPA---EKTPNYIYDAKVQAIGDKYKKSTAQVVLR 251
            ||...|.||:..|:::|||:|||.|||.. ||.   ..:|..:.||.:.::|.:|.|:.||:|||
Human   197 HPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLR 261

  Fly   252 YLIEIGTIPLPKSSNPKRIEENFQIFDFQLDAEDHAILDSYNTGERLIPMTHAIKSKNYPFNIEF 316
            :.|:.|.:.:|||.|.:||:||||||||.|..|:...:::.|...|.:.:........|||:.|:
Human   262 FNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPFHDEY 326

  Fly   317  316
            Human   327  326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10863	NP_647840.1	ARA1	6..304	CDD:223729	129/307 (42%)
		Tas	11..290	CDD:223739	126/288 (44%)
AKR1D1	NP_005980.1	AKR_AKR1D1-3	15..322	CDD:381335	129/308 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.730