Protein Alignment CG10863 and Akr1e1

DIOPT Version :10

• Sequence 1: NP_647840.1
• Gene: CG10863 / 38463
• FlyBaseID: FBgn0027552
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_061347.2
• Gene: Akr1e1 / 56043
• MGIID: 1914758
• Length: 301
• Species: Mus musculus
• Alignment Length: 303
• Identity: 135/303 - (44%)
• Similarity: 186/303 - (61%)
• Gaps: 7/303 - (2%)

  Fly    16 IQSIGLGTYTSLGGDCERATLHAIDVGYRHIDTAYFYENENEVGAAVQRKIAEGVIKREDIHITT 80
            |.::||||:.:..|:...|...||::||||.|.||.|.||:|||..:..||.|||:||||:.:.:
Mouse     4 IPTVGLGTWKASPGEVTDAVKLAINLGYRHFDCAYLYHNESEVGMGISEKIKEGVVKREDLFVVS 68

  Fly    81 KLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPYSYVYRGDNEMMPTDAKGEVELNDIDYLD 145
            ||||..|:...|:.||..||:...|.|:||||:|||..  ::...:.:|.|..|:|..:...:||
Mouse    69 KLWCTCHKKSLVKTACTNTLEALNLDYLDLYLIHWPMG--FKPGEKDIPLDRNGKVIPSHTSFLD 131

  Fly   146 TWREMEKLVELGLTKSIGVSNFNSEQLTRLL--ANCKIKPIHNQIECHPALNQKKLIALCKKNDI 208
            ||..||.||..||.|::||||||.|||.|||  ...:::||.|||||||.|||||||..|.|.::
Mouse   132 TWEAMEDLVFEGLVKNLGVSNFNHEQLERLLDKPGLRVRPITNQIECHPYLNQKKLIDFCHKRNV 196

  Fly   209 VVTAYCPLGRPNPAEKTPNYIYDAKVQAIGDKYKKSTAQVVLRYLIEIGTIPLPKSSNPKRIEEN 273
            .||||.|||......   :.:.|..::.|..|:.||.||:::|:.|:...|.:|||..|.||.||
Mouse   197 SVTAYRPLGGSGGGF---HLMDDTVIRKIAKKHGKSPAQILIRFQIQRNLIVIPKSVTPSRIREN 258

  Fly   274 FQIFDFQLDAEDHAILDSYNTGERLIPMTHAIKSKNYPFNIEF 316
            .|:|||:|..:|...|.|.:...||.........::|||:||:
Mouse   259 IQVFDFELTEKDMEELLSLDKNLRLATFPTTENHQDYPFHIEY 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10863	NP_647840.1	AKR_AKR2E1-5	6..299	CDD:381342	129/284 (45%)
Akr1e1	NP_061347.2	AKR_SF	1..301	CDD:444925	134/301 (45%)