Protein Alignment CG10863 and akr1c8

DIOPT Version :10

• Sequence 1: NP_647840.1
• Gene: CG10863 / 38463
• FlyBaseID: FBgn0027552
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_001004955.1
• Gene: akr1c8 / 448368
• XenbaseID: XB-GENE-5757727
• Length: 324
• Species: Xenopus tropicalis
• Alignment Length: 329
• Identity: 139/329 - (42%)
• Similarity: 191/329 - (58%)
• Gaps: 33/329 - (10%)

  Fly     8 VKHNNGTQIQSIGLGTYT------SLGGDCERATLHAIDVGYRHIDTAYFYENENEVGAAVQRKI 66
            ::.|:|.::..:|.|||.      ||   .|..|..||||||||||:|:||.||.|||.|::.||
 Frog     9 IELNDGHKMPVLGFGTYAPQKFPKSL---AEEGTKVAIDVGYRHIDSAFFYGNEVEVGRAIRAKI 70

  Fly    67 AEGVIKREDIHITTKLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPYSYVYRGDNEMMPTD 131
            |:|.:||||:..|.|||..||.|:||..|..|:|.:..|.|:||:::|.|.. :..|| :.:|.|
 Frog    71 ADGTVKREDVFYTGKLWSTFHTPERVRPALEKSLNDLQLDYMDLFIIHIPVE-LKPGD-DPLPLD 133

  Fly   132 AKGEVELNDIDYLDTWREMEKLVELGLTKSIGVSNFNSEQLTRLL--ANCKIKPIHNQIECHPAL 194
            ..|:...::.|..|||:.:||..:.||.:||||||||.:||..:|  ...|.||:.||:|||..|
 Frog   134 ENGKFIYHNTDIRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPGLKYKPVCNQVECHVYL 198

  Fly   195 NQKKLIALCKKNDIVVTAYCPLGR--------PNPAEKTPNYIYDAKVQAIGDKYKKSTAQVVLR 251
            ||.||:..||..|||:.|:..||.        ||    .|..:.|..:.||..|:..:.|||.:|
 Frog   199 NQSKLLEFCKSKDIVLVAFGVLGSSRDESWIDPN----LPVLLEDPVLNAIAKKHNCTPAQVAMR 259

  Fly   252 YLIEIGTIPLPKSSNPKRIEENFQIFDFQLDAEDHAILDSYNTGER--LIPM--THAIKSKNYPF 312
            ||::.|.:.|.||..|.||::|||:|:..|||||...:|..|...|  ..||  .|    ..|||
 Frog   260 YLLQRGVVVLVKSFTPARIQQNFQVFNVHLDAEDMRNVDGINRNLRYDYAPMWSDH----PKYPF 320

  Fly   313 NIEF 316
            :.|:
 Frog   321 HEEY 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10863	NP_647840.1	AKR_AKR2E1-5	6..299	CDD:381342	132/308 (43%)
akr1c8	NP_001004955.1	AKR_AKR1C1-35	8..306	CDD:381334	131/305 (43%)