Protein Alignment CG10863 and Akr1c19

DIOPT Version :10

• Sequence 1: NP_647840.1
• Gene: CG10863 / 38463
• FlyBaseID: FBgn0027552
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_001013807.2
• Gene: Akr1c19 / 432720
• MGIID: 2653678
• Length: 323
• Species: Mus musculus
• Alignment Length: 325
• Identity: 140/325 - (43%)
• Similarity: 192/325 - (59%)
• Gaps: 11/325 - (3%)

  Fly     1 MSSKIPYVKHNNGTQIQSIGLGTY--TSLGGDCERATLH-AIDVGYRHIDTAYFYENENEVGAAV 62
            ||||...||.|:|..|.::|.|||  ..:..:.....:| |::.|:|||||||.|:.||.||.|:
Mouse     1 MSSKQQCVKLNDGNFIPALGFGTYKPEEVNENKPLEAIHLALEAGFRHIDTAYVYQTENHVGQAI 65

  Fly    63 QRKIAEGVIKREDIHITTKLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPYSYVYRGDNEM 127
            :.|||.|::|||||.:||||||.||.|:.|.....|:|:|..|.|.||||:|:|..  .:...::
Mouse    66 RSKIAAGLVKREDIFLTTKLWCTFHRPELVRSNLEKSLKNLQLDYADLYLIHYPVQ--MKPGEDL 128

  Fly   128 MPTDAKGEVELNDIDYLDTWREMEKLVELGLTKSIGVSNFNSEQLTRLL--ANCKIKPIHNQIEC 190
            .|.|..|:...:.:|...||..|||..:.||.||||||||||.||.::|  ...|.||:.||:||
Mouse   129 FPEDEHGKTLFDTVDICATWEAMEKCKDAGLVKSIGVSNFNSRQLEKILNKPGLKYKPVCNQVEC 193

  Fly   191 HPALNQKKLIALCKKNDIVVTAYCPLGRPNPAE----KTPNYIYDAKVQAIGDKYKKSTAQVVLR 251
            |..|||:||:..||..|||:.|||.||...|..    .:|..:.|..:..:..|:|:|.||:.||
Mouse   194 HLYLNQRKLLNYCKSKDIVLVAYCALGSQRPKRWVDPSSPVLLNDPILCDMAKKHKRSPAQIALR 258

  Fly   252 YLIEIGTIPLPKSSNPKRIEENFQIFDFQLDAEDHAILDSYNTGERLIPMTHAIKSKNYPFNIEF 316
            |.::.|.:.|.:|.....|:||.|:|:|:|.:||..||||.:...|..|.........|||:.||
Mouse   259 YHLQRGIVVLAQSYKENEIKENIQVFEFELPSEDMKILDSLDRNLRYAPAPFGEGHPEYPFSDEF 323

  Fly   317  316
            Mouse   324  323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10863	NP_647840.1	AKR_AKR2E1-5	6..299	CDD:381342	130/301 (43%)
Akr1c19	NP_001013807.2	AKR_AKR1C1-35	6..308	CDD:381334	130/303 (43%)