Protein Alignment CG10863 and Akr1c12

DIOPT Version :10

• Sequence 1: NP_647840.1
• Gene: CG10863 / 38463
• FlyBaseID: FBgn0027552
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_001014262.3
• Gene: Akr1c12 / 364773
• RGDID: 1359406
• Length: 323
• Species: Rattus norvegicus
• Alignment Length: 326
• Identity: 142/326 - (43%)
• Similarity: 186/326 - (57%)
• Gaps: 13/326 - (3%)

  Fly     1 MSSKIPYVKHNNGTQIQSIGLGTY----TSLGGDCERATLHAIDVGYRHIDTAYFYENENEVGAA 61
            ||||:..||.|:|..|.::|.|||    .......|.|.| ||||||||||||..|:.|.|:|.|
  Rat     1 MSSKLHCVKLNDGHFIPALGFGTYKPKEVPKSKSLEAAHL-AIDVGYRHIDTASAYQVEEEIGQA 64

  Fly    62 VQRKIAEGVIKREDIHITTKLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPYSYVYRGDNE 126
            :|.||..||:||:|:.|||||||.....:.|..|..|:|:|..|.||||:|:|:|..  .:...:
  Rat    65 IQSKIKAGVVKRKDMFITTKLWCSCFRTEMVRPALEKSLKNLQLDYVDLFLIHYPVP--IKSSVD 127

  Fly   127 MMPTDAKGEVELNDIDYLDTWREMEKLVELGLTKSIGVSNFNSEQLTRLL--ANCKIKPIHNQIE 189
            ..|.|.||:..|:.:|:.|||..:||..:.||.|||||||||.:||.|||  ...|.||:.||:|
  Rat   128 ESPLDEKGKFLLDTVDFCDTWEMLEKCKDAGLVKSIGVSNFNHKQLERLLNKPGLKYKPVCNQVE 192

  Fly   190 CHPALNQKKLIALCKKNDIVVTAYCPLGRPNPAE----KTPNYIYDAKVQAIGDKYKKSTAQVVL 250
            ||..|||.||:..||..|||:.||..||.....|    .:|..:.|..:..:..|.|:|.|.:.|
  Rat   193 CHLYLNQSKLLDYCKSKDIVLVAYGALGTQRYKEWVDQNSPVLLDDPILCDVAKKNKRSPALIAL 257

  Fly   251 RYLIEIGTIPLPKSSNPKRIEENFQIFDFQLDAEDHAILDSYNTGERLIPMTHAIKSKNYPFNIE 315
            |||.:.|.:||.:|.....:.||.|:|:|||..||...||..|...|.:..........|||:.|
  Rat   258 RYLFQRGVVPLAQSFKENEMRENLQVFEFQLSPEDMKTLDGLNKNFRYLSAEFLADHPEYPFSEE 322

  Fly   316 F 316
            :
  Rat   323 Y 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10863	NP_647840.1	AKR_AKR2E1-5	6..299	CDD:381342	134/302 (44%)
Akr1c12	NP_001014262.3	AKR_AKR1C1-35	6..308	CDD:381334	134/304 (44%)