Protein Alignment CG10863 and Akr1c2

DIOPT Version :10

• Sequence 1: NP_647840.1
• Gene: CG10863 / 38463
• FlyBaseID: FBgn0027552
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_001427047.1
• Gene: Akr1c2 / 291283
• RGDID: 1311841
• Length: 323
• Species: Rattus norvegicus
• Alignment Length: 327
• Identity: 126/327 - (38%)
• Similarity: 183/327 - (55%)
• Gaps: 15/327 - (4%)

  Fly     1 MSSKIPYVKHNNGTQIQSIGLGTYTSLGGD-----CERATLHAIDVGYRHIDTAYFYENENEVGA 60
            |:||...||.|:|..|..:|.|  |::..:     .:..|..|||.|:.|.|:|:.|..|:.||.
  Rat     1 MNSKCHCVKLNDGHFIPVLGFG--TAMPSELPKSKAKEVTKIAIDAGFHHFDSAFVYNTEDHVGE 63

  Fly    61 AVQRKIAEGVIKREDIHITTKLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPYSYVYRGDN 125
            |::.|||.|..:||||..|:||||....|:.|..:...:|:...|.||||||:|:|.: :..||
  Rat    64 AIREKIANGTTRREDIFYTSKLWCTSLHPELVRSSLECSLKKLQLDYVDLYLIHFPMA-LKPGD- 126

  Fly   126 EMMPTDAKGEVELNDIDYLDTWREMEKLVELGLTKSIGVSNFNSEQLTRLL--ANCKIKPIHNQI 188
            |..|.|..|::..:.:|...||..|||..:.||.|||||||||..||.::|  ...|.||:.||:
  Rat   127 ENFPVDEHGKLLFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKYKPVCNQV 191

  Fly   189 ECHPALNQKKLIALCKKNDIVVTAYCPLG--RPN--PAEKTPNYIYDAKVQAIGDKYKKSTAQVV 249
            |||..|||.||:..||.|.|::.||..||  |.|  ..:.:|..:.:..:.::..||.::.|.:.
  Rat   192 ECHLYLNQMKLLDFCKTNGIILVAYGVLGTQRYNGWVDQNSPVLLNEPVLSSMAKKYNQTPALIA 256

  Fly   250 LRYLIEIGTIPLPKSSNPKRIEENFQIFDFQLDAEDHAILDSYNTGERLIPMTHAIKSKNYPFNI 314
            ||:.::.|.:.|..|...:||:||.::|:|||..||..:||..|...|.|.........|:||..
  Rat   257 LRHQLQRGIVVLNTSLKEERIKENMKVFEFQLSPEDMKVLDDLNRNLRYIAGGIFEGHPNFPFLD 321

  Fly   315 EF 316
            |:
  Rat   322 EY 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10863	NP_647840.1	AKR_AKR2E1-5	6..299	CDD:381342	118/303 (39%)
Akr1c2	NP_001427047.1	None