Protein Alignment CG10863 and AKR1B1

DIOPT Version :9

• Sequence 1: NP_647840.1
• Gene: CG10863 / 38463
• FlyBaseID: FBgn0027552
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_001619.1
• Gene: AKR1B1 / 231
• HGNCID: 381
• Length: 316
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 146/311 - (46%)
• Similarity: 201/311 - (64%)
• Gaps: 7/311 - (2%)

  Fly    11 NNGTQIQSIGLGTYTSLGGDCERATLHAIDVGYRHIDTAYFYENENEVGAAVQRKIAEGVIKRED 75
            |||.::..:||||:.|..|....|...||||||||||.|:.|:||||||.|:|.|:.|.|:|||:
Human     8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREE 72

  Fly    76 IHITTKLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPYSYVYRGDNEMMPTDAKGEVELND 140
            :.|.:||||.:||...|:.||:|||.:..|.|:||||:|||..  ::...|..|.|..|.|..:|
Human    73 LFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG--FKPGKEFFPLDESGNVVPSD 135

  Fly   141 IDYLDTWREMEKLVELGLTKSIGVSNFNSEQLTRLL--ANCKIKPIHNQIECHPALNQKKLIALC 203
            .:.||||..||:||:.||.|:||:||||..|:..:|  ...|.||..|||||||.|.|:|||..|
Human   136 TNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYC 200

  Fly   204 KKNDIVVTAYCPLG---RPNPAEKTPNYIYDAKVQAIGDKYKKSTAQVVLRYLIEIGTIPLPKSS 265
            :...||||||.|||   ||....:.|:.:.|.:::||..|:.|:||||::|:.::...:.:|||.
Human   201 QSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSV 265

  Fly   266 NPKRIEENFQIFDFQLDAEDHAILDSYNTGERLIPMTHAIKSKNYPFNIEF 316
            .|:||.|||::|||:|.::|...|.|||...|:..:......|:|||:.||
Human   266 TPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPFHEEF 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10863	NP_647840.1	ARA1	6..304	CDD:223729	140/297 (47%)
		Tas	11..290	CDD:223739	135/283 (48%)
AKR1B1	NP_001619.1	AKR_AKR1B1-19	10..316	CDD:381333	142/307 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.730