Protein Alignment CG10863 and AKR1C1

DIOPT Version :9

• Sequence 1: NP_647840.1
• Gene: CG10863 / 38463
• FlyBaseID: FBgn0027552
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_001344.2
• Gene: AKR1C1 / 1645
• HGNCID: 384
• Length: 323
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 137/325 - (42%)
• Similarity: 194/325 - (59%)
• Gaps: 11/325 - (3%)

  Fly     1 MSSKIPYVKHNNGTQIQSIGLGTYTSL---GGDCERATLHAIDVGYRHIDTAYFYENENEVGAAV 62
            |.||...||.|:|..:..:|.|||...   ......||..||:.|:||||:|:.|.||.:||.|:
Human     1 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65

  Fly    63 QRKIAEGVIKREDIHITTKLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPYSYVYRGDNEM 127
            :.|||:|.:|||||..|:||||:.|.|:.|..|..::|:|..|.||||||:|:|.| |..|: |:
Human    66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS-VKPGE-EV 128

  Fly   128 MPTDAKGEVELNDIDYLDTWREMEKLVELGLTKSIGVSNFNSEQLTRLL--ANCKIKPIHNQIEC 190
            :|.|..|::..:.:|...||..:||..:.||.|||||||||..||..:|  ...|.||:.||:||
Human   129 IPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 193

  Fly   191 HPALNQKKLIALCKKNDIVVTAYCPLG--RPNP--AEKTPNYIYDAKVQAIGDKYKKSTAQVVLR 251
            ||..||:||:..||..|||:.||..||  |..|  ...:|..:.|..:.|:..|:|::.|.:.||
Human   194 HPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALR 258

  Fly   252 YLIEIGTIPLPKSSNPKRIEENFQIFDFQLDAEDHAILDSYNTGERLIPMTHAIKSKNYPFNIEF 316
            |.::.|.:.|.||.|.:||.:|.|:|:|||.:|:...:|..|...|.:.:.......||||:.|:
Human   259 YQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY 323

  Fly   317  316
            Human   324  323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10863	NP_647840.1	ARA1	6..304	CDD:223729	129/306 (42%)
		Tas	11..290	CDD:223739	124/287 (43%)
AKR1C1	NP_001344.2	AKR_AKR1C1-35	6..308	CDD:381334	129/303 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.730