Protein Alignment CG10863 and Akr1b7

DIOPT Version :10

• Sequence 1: NP_647840.1
• Gene: CG10863 / 38463
• FlyBaseID: FBgn0027552
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_033861.2
• Gene: Akr1b7 / 11997
• MGIID: 101918
• Length: 316
• Species: Mus musculus
• Alignment Length: 315
• Identity: 140/315 - (44%)
• Similarity: 195/315 - (61%)
• Gaps: 7/315 - (2%)

  Fly     7 YVKHNNGTQIQSIGLGTYTSLGGDCERATLHAIDVGYRHIDTAYFYENENEVGAAVQRKIAEGVI 71
            :|:.:...::..:||||:.|..|..:.|...|||.||||||.||.|.||||||.|:|.||.|..:
Mouse     4 FVELSTKAKMPLVGLGTWKSSPGQVKEAVKAAIDAGYRHIDCAYVYHNENEVGEAIQEKIKENAV 68

  Fly    72 KREDIHITTKLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPYSYVYRGDNEMMPTDAKGEV 136
            ||||:.|.:|||..|.|...|:.|.:.||.:..|.|:||||:|||..  ::..|.::|.|.||:|
Mouse    69 KREDLFIVSKLWATFFEKSLVKKAFQNTLSDLKLDYLDLYLVHWPQG--FQAGNALLPKDNKGKV 131

  Fly   137 ELNDIDYLDTWREMEKLVELGLTKSIGVSNFNSEQLTRLL--ANCKIKPIHNQIECHPALNQKKL 199
            .|:...:||.|..||:||:.||.|::|:||||..|:.|||  ...|.||:.||||.||.|.|:||
Mouse   132 LLSKSTFLDAWEAMEELVDQGLVKALGISNFNHFQIERLLNKPGLKHKPVTNQIESHPYLTQEKL 196

  Fly   200 IALCKKNDIVVTAYCPLG---RPNPAEKTPNYIYDAKVQAIGDKYKKSTAQVVLRYLIEIGTIPL 261
            |..|:...|.||||.|||   ||....:.|..:...|::.|..|:||:.|||::|:.::...:.:
Mouse   197 IQYCQSKGIAVTAYSPLGSPDRPYAKPEDPVVMEIPKIKEIAAKHKKTVAQVLIRFHVQRNVVVI 261

  Fly   262 PKSSNPKRIEENFQIFDFQLDAEDHAILDSYNTGERLIPMTHAIKSKNYPFNIEF 316
            |||..|.||:||.|:|||||..||.|.:.|:|...|...:..|...::|||:.|:
Mouse   262 PKSVTPSRIQENLQVFDFQLSEEDMAAILSFNRNWRACDLLDARTEEDYPFHEEY 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10863	NP_647840.1	AKR_AKR2E1-5	6..299	CDD:381342	135/296 (46%)
Akr1b7	NP_033861.2	AKR_AKR1B1-19	10..316	CDD:381333	138/307 (45%)