Protein Alignment CG10863 and AKR1A1

DIOPT Version :9

• Sequence 1: NP_647840.1
• Gene: CG10863 / 38463
• FlyBaseID: FBgn0027552
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_001189342.1
• Gene: AKR1A1 / 10327
• HGNCID: 380
• Length: 325
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 126/317 - (39%)
• Similarity: 190/317 - (59%)
• Gaps: 17/317 - (5%)

  Fly    11 NNGTQIQSIGLGTYTSLGGDCERATLHAIDVGYRHIDTAYFYENENEVGAAVQRKIAEG-VIKRE 74
            :.|.::..|||||:.|..|..:.|..:|:.|||||||.|..|.||.|:|.|::..:..| .:.||
Human     9 HTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPRE 73

  Fly    75 DIHITTKLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPYSYVYRGDNEMMPTDAKGEVELN 139
            ::.:|:|||...|.|:.||.|.||||.:..|:|:|||||||||:: .||||. .|.:|.|.:..:
Human    74 ELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF-ERGDNP-FPKNADGTICYD 136

  Fly   140 DIDYLDTWREMEKLVELGLTKSIGVSNFNSEQLTRLLANCKIKPIHNQIECHPALNQKKLIALCK 204
            ...|.:||:.:|.||..||.:::|:|||||.|:..:|:...::|...|:||||.|.|.:|||.|:
Human   137 STHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQ 201

  Fly   205 KNDIVVTAYCPLGRPNPAEKTPN---YIYDAKVQAIGDKYKKSTAQVVLRYLIEIGTIPLPKSSN 266
            ...:.||||.|||..:.|.:.|:   .:.:..|.|:.:||.:|.||::||:.::...|.:|||..
Human   202 ARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSIT 266

  Fly   267 PKRIEENFQIFDFQLDAEDHAILDSYNTGER-LIPMTHAIKSKN---------YPFN 313
            |.||.:|.::|||....|:...|::.|...| ::||. .:..|.         ||||
Human   267 PSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPML-TVDGKRVPRDAGHPLYPFN 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10863	NP_647840.1	ARA1	6..304	CDD:223729	121/297 (41%)
		Tas	11..290	CDD:223739	116/282 (41%)
AKR1A1	NP_001189342.1	ARA1	6..303	CDD:223729	120/295 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.690