Protein Alignment CG12766 and AKR1C3

DIOPT Version :9

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_001240837.1
• Gene: AKR1C3 / 8644
• HGNCID: 386
• Length: 323
• Species: Homo sapiens
• Alignment Length: 321
• Identity: 136/321 - (42%)
• Similarity: 183/321 - (57%)
• Gaps: 25/321 - (7%)

  Fly    10 KHNDGTHIQGIGLGTFASTEGDCERAV---LHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGV 71
            |.|||..:..:|.||:|..|....:|:   ..||:.|:||||:|:.|.||.:||.|:|.|||:|.
Human     9 KLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGS 73

  Fly    72 IKREDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGE 136
            :||||||.|:|||..||.||.|..|...:||...||||||||||.|.|.|  ...||.|.|.||:
Human    74 VKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK--PGEELSPTDENGK 136

  Fly   137 VELVDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLL--ANCKIKPIHNQIEVHPALDQKK 199
            |....:|...||.||||..|.||.|||||||||..||..:|  ...|.||:.||:|.||..::.|
Human   137 VIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSK 201

  Fly   200 LIALCKKNGILVTAFSPLGRHN----AELRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTI 260
            |:..||...|::.|:|.||...    .:..:|..:.|..:.|:|.|:.::.|.:.:||.::.|.:
Human   202 LLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVV 266

  Fly   261 PLPKSSNPKRIEENFNVFDFKLDAEDHAILDS------YHNGERVA-HARQAIKSKYYPFN 314
            .|.||.|.:||.:|..||:|:|.|||...:|.      |.|.:..| |..       ||::
Human   267 VLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPN-------YPYS 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	ARA1	5..298	CDD:223729	132/302 (44%)
		Tas	12..299	CDD:223739	131/301 (44%)
AKR1C3	NP_001240837.1	ARA1	9..305	CDD:223729	130/297 (44%)
		Tas	17..297	CDD:223739	125/281 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.730