Protein Alignment CG12766 and AKR7A2

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_003680.2
• Gene: AKR7A2 / 8574
• HGNCID: 389
• Length: 359
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 56/244 - (22%)
• Similarity: 91/244 - (37%)
• Gaps: 74/244 - (30%)

  Fly    35 AVLHAIDVGYRHIDTAYFYGN-EAEV----------GAAVRKKIAEGVIKREDIFITTKL--WCN 86
            ||...::.|:..:|||:.|.: ::|.          |...|.|||            ||.  |..
Human    59 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIA------------TKANPWDG 111

  Fly    87 FH-EPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGEVELVDIDYLDTWGA 150
            .. :|:.|......:||.:....|||:.:|.|              |....||       :|..|
Human   112 KSLKPDSVRSQLETSLKRLQCPQVDLFYLHAP--------------DHGTPVE-------ETLHA 155

  Fly   151 MEKLVDLGLTKSIGVSNFNEEQLTRLLANCK----IKP-----IHN----QIEVHPALDQKKLIA 202
            .::|...|....:|:||:...::..:...||    |.|     ::|    |:|.       :|..
Human   156 CQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVET-------ELFP 213

  Fly   203 LCKKNGILVTAFSPLGRHNAELRTPTFMY---DGKVQAIADKYNKSIAQ 248
            ..:..|:...|::||.   ..|.|..:.|   ||| |.:...:..|.|:
Human   214 CLRHFGLRFYAYNPLA---GGLLTGKYKYEDKDGK-QPVGRFFGNSWAE 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	56/244 (23%)
AKR7A2	NP_003680.2	AKR_AKR7A1-5	38..347	CDD:381301	56/244 (23%)