Protein Alignment CG12766 and GRE3

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_011972.1
• Gene: GRE3 / 856504
• SGDID: S000001146
• Length: 327
• Species: Saccharomyces cerevisiae
• Alignment Length: 293
• Identity: 110/293 - (37%)
• Similarity: 168/293 - (57%)
• Gaps: 22/293 - (7%)

  Fly    12 NDGTHIQGIGLGTFASTEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGVIKRED 76
            |:|..:..:|||.:...:..|...:..||.:|||..|.|..||||.|||..:||.|:||::.|:|
Yeast     8 NNGLKMPLVGLGCWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAISEGLVSRKD 72

  Fly    77 IFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIP--------KDA 133
            ||:.:|||.|||.|:.|:.|.:|||.::||||:|||.||:|.::||....|..|        .:.
Yeast    73 IFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEEKYPPGFYTGADDEK 137

  Fly   134 NGEVELVDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLLANCKIKPIHNQIEVHPALDQK 198
            .|.:....:..:||:.|:|:.||.||.||||||||....:..||..|:|||:..|||.||.|.|:
Yeast   138 KGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDLLRGCRIKPVALQIEHHPYLTQE 202

  Fly   199 KLIALCKKNGILVTAFSPLGRHN---AELR----TPTFMYDGKVQAIADKY-NKSIAQVVIRYVI 255
            .|:..||.:.|.|.|:|..|..:   .:|:    |||...:..::.::..: ..:.:||::|:..
Yeast   203 HLVEFCKLHDIQVVAYSSFGPQSFIEMDLQLAKTTPTLFENDVIKKVSQNHPGSTTSQVLLRWAT 267

  Fly   256 ELGTIPLPKSSNPKR------IEENFNVFDFKL 282
            :.|...:||||..:|      ||:.|.:.:.:|
Yeast   268 QRGIAVIPKSSKKERLLGNLEIEKKFTLTEQEL 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	110/293 (38%)
GRE3	NP_011972.1	AKR_SF	3..318	CDD:444925	110/293 (38%)