Protein Alignment CG12766 and AAD10

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_012689.1
• Gene: AAD10 / 853620
• SGDID: S000003916
• Length: 288
• Species: Saccharomyces cerevisiae
• Alignment Length: 272
• Identity: 52/272 - (19%)
• Similarity: 93/272 - (34%)
• Gaps: 80/272 - (29%)

  Fly    74 REDIFITTKL----------------WCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKY 122
            |:.|.|.||.                :|..|: ..:..:.|.:|:.:..|::|:..:||   :.|
Yeast     7 RDQIVIATKFTTDYKGYDVGKGKSANFCGNHK-RSLHVSVRDSLRKLQTDWIDILYVHW---WDY 67

  Fly   123 RGDNELIPKDANGEVELVDIDYLDTWGAMEKLVDLGLTKSIGVSN-------------------- 167
            ....|          |::|        ::..||..|....:|||:
Yeast    68 MSSIE----------EVMD--------SLHILVQQGKVLYLGVSDTPAWVVSAANYYATSHGKTP 114

  Fly   168 FNEEQ-----LTRLLANCKIKPI--HNQIEVHP-------ALDQKKLIALCKKNGI-LVTAFSPL 217
            |:..|     |.|.... .|.|:  |..:.:.|       ....||.:...||.|. |.|.|...
Yeast   115 FSIYQGKWNVLNRDFER-DIIPMARHFGMALAPWDVMGGGRFQSKKAVEERKKKGEGLRTFFGTS 178

  Fly   218 GRHNAELRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELG--TIPLPKSSNPKRIEENFNVFDF 280
            .:.:.|::    :.:..::...:...:|:..:.|.||....  ..||......:.:::|......
Yeast   179 EQTDMEVK----ISEALLKVAEEHGTESVTAIAIAYVRSKAKHVFPLVGGRKIEHLKQNIEALSI 239

  Fly   281 KLDAEDHAILDS 292
            ||..|....|:|
Yeast   240 KLTPEQIKYLES 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	52/272 (19%)
AAD10	NP_012689.1	AKR_SF	<1..250	CDD:444925	50/269 (19%)