Protein Alignment CG12766 and AAD3

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_010032.1
• Gene: AAD3 / 850471
• SGDID: S000000704
• Length: 363
• Species: Saccharomyces cerevisiae
• Alignment Length: 317
• Identity: 59/317 - (18%)
• Similarity: 109/317 - (34%)
• Gaps: 106/317 - (33%)

  Fly    41 DVGYRHIDTAYFYGNEAE---VGAAVRKKIAEGVIKREDIFITTKL----------------WCN 86
            :.|...||.|....||..   :|..::.:..     |:.|.|.||.                :|.
Yeast    61 EAGGNFIDAANNCQNEQSEEWIGEWIQSRRL-----RDQIVIATKFIKSDKKYKAGESNTANYCG 120

  Fly    87 FHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGEVELVDIDYLDTWGAM 151
            .|: ..:..:.|.:|:.:..|::|:..:||   :.|....|               :::|   ::
Yeast   121 NHK-RSLHVSVRDSLRKLQTDWIDILYVHW---WDYMSSIE---------------EFMD---SL 163

  Fly   152 EKLVDLGLTKSIGVSN--------------------FNEEQ-----LTRLLANCKIKPI--HNQI 189
            ..||..|....:|||:                    |:..|     |.|.... .|.|:  |..:
Yeast   164 HILVQQGKVLYLGVSDTPAWVVSAANYYATSYGKTPFSIYQGKWNVLNRDFER-DIIPMARHFGM 227

  Fly   190 EVHP-------ALDQKKLIALCKKNGILVTAFSPLGRH-NAELRTPTFMYDGKVQAIADKY-NKS 245
            .:.|       ....||.:...:|||..:.:|...... :||::     ....:..||::: .:|
Yeast   228 ALAPWDVMGGGRFQSKKAMEERRKNGEGIRSFVGASEQTDAEIK-----ISEALAKIAEEHGTES 287

  Fly   246 IAQVVIRYV----------IELGTIPLPKSSNPKRIEENFNVFDFKLDAEDHAILDS 292
            :..:.|.||          :|.|.|        :.::||.......|..::...|:|
Yeast   288 VTAIAIAYVRSKAKNFFPSVEGGKI--------EDLKENIKALSIDLTPDNIKYLES 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	59/317 (19%)
AAD3	NP_010032.1	AKR_AKR9A3_9B1-4	17..335	CDD:381373	57/314 (18%)