Protein Alignment CG12766 and Akr1c6

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_085114.1
• Gene: Akr1c6 / 83702
• MGIID: 1933427
• Length: 323
• Species: Mus musculus
• Alignment Length: 311
• Identity: 137/311 - (44%)
• Similarity: 188/311 - (60%)
• Gaps: 11/311 - (3%)

  Fly    12 NDGTHIQGIGLGTFASTE---GDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGVIK 73
            :||..|..:|.||:|..|   .....|...|||.|:||||:|..|.||.|||.|:|.|||:|.:|
Mouse    11 SDGHFIPILGFGTYAPQEVPKSKATEATKIAIDAGFRHIDSASMYQNEKEVGLAIRSKIADGTVK 75

  Fly    74 REDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGEVE 138
            |||||.|:|:||.||.||.|.....::||.:.||||||||||:|.:.| .|:|.| |||.||::.
Mouse    76 REDIFYTSKVWCTFHRPELVRVCLEQSLKQLQLDYVDLYLIHFPMAMK-PGENYL-PKDENGKLI 138

  Fly   139 LVDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLL--ANCKIKPIHNQIEVHPALDQKKLI 201
            ...:|..|||.||||..|.||.|||||||||..||.::|  ...|.||:.||:|.||.|:|.||:
Mouse   139 YDAVDICDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILKKPGLKYKPVCNQVECHPYLNQGKLL 203

  Fly   202 ALCKKNGILVTAFSPLGRHN----AELRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTIPL 262
            ..|:...|::.|:|.||.|.    .:..:|..:.:..:.::|.|||::.|.:.:||.::.|.:.|
Mouse   204 DFCRSKDIVLVAYSALGSHREKQWVDQSSPVLLDNPVLGSMAKKYNRTPALIALRYQLQRGVVVL 268

  Fly   263 PKSSNPKRIEENFNVFDFKLDAEDHAILDSYHNGERVAHARQAIKSKYYPF 313
            .||.:.|||:||..||:|:|.:||..:||..:...|............:||
Mouse   269 AKSFSEKRIKENMQVFEFQLTSEDMKVLDDLNKNIRYISGSSFKDHPDFPF 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	134/295 (45%)
Akr1c6	NP_085114.1	AKR_AKR1C1-35	6..308	CDD:381334	135/298 (45%)