DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12766 and AKR4C8

DIOPT Version :9

Sequence 1:	NP_647839.1	Gene:	CG12766 / 38462	FlyBaseID:	FBgn0035476	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_565871.1	Gene:	AKR4C8 / 818353	AraportID:	AT2G37760	Length:	311	Species:	Arabidopsis thaliana

Alignment Length:	276	Identity:	118/276 - (42%)
Similarity:	168/276 - (60%)	Gaps:	13/276 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 YFKHNDGTHIQGIGLGTFASTEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGVI 72
            :|:.|.|..:..:||||:|..    ..|:..||.:||||||.|..||||.|:|..::|.|.:|.:
plant     7 FFELNTGAKLPCVGLGTYAMV----ATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGDGFV 67

  Fly    73 KREDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGEV 137
            |||::|||:|||.|.|.||.|..|..|||:::.:|||||||||||.|.|   ...|:|...
plant    68 KREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLK---KESLMPTPE---- 125

  Fly   138 ELVDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLLANCKIKPIHNQIEVHPALDQKKLIA 202
            .|...|...||.|||.|.|.|..::||||||:.::||.||...::.|..||:|.||...|:.|..
plant   126 MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVARVTPAVNQVECHPVWQQQGLHE 190

  Fly   203 LCKKNGILVTAFSPLG-RHNAELRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTIPLPKSS 266
            |||..|:.::.:|||| :...|:|... :.:..|..:|:|..|:.|||.:|:.::.|...|||||
plant   191 LCKSKGVHLSGYSPLGSQSKGEVRLKV-LQNPIVTEVAEKLGKTTAQVALRWGLQTGHSVLPKSS 254

  Fly   267 NPKRIEENFNVFDFKL 282
            :..|::||.:|||:.:
plant   255 SGARLKENLDVFDWSI 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	ARA1	5..298	CDD:223729	118/276 (43%)
CG12766	NP_647839.1	Tas	12..299	CDD:223739	117/272 (43%)
AKR4C8	NP_565871.1	AKR_AKR4C1-15	6..288	CDD:381351	118/276 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	244	1.000	Domainoid score	I557
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	248	1.000	Inparanoid score	I1036
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	1	1.000	-	-		otm2923
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.780