Protein Alignment CG12766 and Akr1a1

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_112262.1
• Gene: Akr1a1 / 78959
• RGDID: 68346
• Length: 325
• Species: Rattus norvegicus
• Alignment Length: 314
• Identity: 131/314 - (41%)
• Similarity: 193/314 - (61%)
• Gaps: 27/314 - (8%)

  Fly    20 IGLGTFASTEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEG-VIKREDIFITTKL 83
            |||||:.|..|..:.|:.:|:.|||||||.|..||||.|:|.|:::.:..| .:.||::|:|:||
  Rat    17 IGLGTWKSEPGQVKAAIKYALSVGYRHIDCASVYGNETEIGEALKESVGAGKAVPREELFVTSKL 81

  Fly    84 WCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGEVELVDIDYLDTW 148
            |...|.||.||.|.||||.::.|:|:||||:|||:::: ||||. .||:|:|.|:.....|.:||
  Rat    82 WNTKHHPEDVEPAVRKTLADLQLEYLDLYLMHWPYAFE-RGDNP-FPKNADGTVKYDSTHYKETW 144

  Fly   149 GAMEKLVDLGLTKSIGVSNFNEEQLTRLLANCKIKPIHNQIEVHPALDQKKLIALCKKNGILVTA 213
            .|:|.||..||.|::|:|||:..|:..:|:...::|...|:|.||.|.|.:|||.|:..|:.|||
  Rat   145 KALEALVAKGLVKALGLSNFSSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTA 209

  Fly   214 FSPLG------RHNAELRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTIPLPKSSNPKRIE 272
            :||||      ||..|   |..:.:..|.|:|:|:.:|.||:::|:.::...|.:|||..|.||.
  Rat   210 YSPLGSSDRAWRHPDE---PVLLEEPVVLALAEKHGRSPAQILLRWQVQRKVICIPKSITPSRIL 271

  Fly   273 ENFNVFDFKLDAEDHAILDSYH------------NGERVAHARQAIKSKYYPFN 314
            :|..||||....|:...||:.:            :|:||  .|.| ....||||
  Rat   272 QNIQVFDFTFSPEEMKQLDALNKNWRYIVPMITVDGKRV--PRDA-GHPLYPFN 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	123/297 (41%)
Akr1a1	NP_112262.1	AKR_AKR1A1-4	8..312	CDD:381332	125/301 (42%)