Protein Alignment CG12766 and Akr1c21

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_084177.2
• Gene: Akr1c21 / 77337
• MGIID: 1924587
• Length: 323
• Species: Mus musculus
• Alignment Length: 298
• Identity: 119/298 - (39%)
• Similarity: 171/298 - (57%)
• Gaps: 15/298 - (5%)

  Fly    12 NDGTHIQGIGLGTFASTEGDCERAVLH-----AIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGV 71
            |||..|..:|.||....|  |.::...     |||.|:.|.|:|..|..|..||.|:|.|||:|.
Mouse    11 NDGNFIPVLGFGTALPLE--CPKSKAKELTKIAIDAGFHHFDSASVYNTEDHVGEAIRSKIADGT 73

  Fly    72 IKREDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGE 136
            ::|||||.|:|:||....||.|..:..::|:.:..|||||||||:|.:.|...:|  .|.|.:|:
Mouse    74 VRREDIFYTSKVWCTSLHPELVRASLERSLQKLQFDYVDLYLIHYPMALKPGEEN--FPVDEHGK 136

  Fly   137 VELVDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLL--ANCKIKPIHNQIEVHPALDQKK 199
            :....:|...||.||||..|.||||||||||||..||..:|  ...|.||:.||:|.||.|:|.|
Mouse   137 LIFDRVDLCATWEAMEKCKDAGLTKSIGVSNFNYRQLEMILNKPGLKYKPVCNQVECHPYLNQMK 201

  Fly   200 LIALCKKNGILVTAFSPLGRHN----AELRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTI 260
            |:..||...|::.|:..||...    .:..:|..:.:..:.::|.|||::.|.:.:||.::.|.:
Mouse   202 LLDFCKSKDIVLVAYGVLGTQRYGGWVDQNSPVLLDEPVLGSMAKKYNRTPALIALRYQLQRGIV 266

  Fly   261 PLPKSSNPKRIEENFNVFDFKLDAEDHAILDSYHNGER 298
            .|..|...:||:||..||:|:|.:||..:||..:...|
Mouse   267 VLNTSLKEERIKENMQVFEFQLSSEDMKVLDGLNRNMR 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	119/298 (40%)
Akr1c21	NP_084177.2	AKR_AKR1C1-35	6..308	CDD:381334	119/298 (40%)