Protein Alignment CG12766 and Akr1cl

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_081858.2
• Gene: Akr1cl / 70861
• MGIID: 1918111
• Length: 322
• Species: Mus musculus
• Alignment Length: 315
• Identity: 141/315 - (44%)
• Similarity: 190/315 - (60%)
• Gaps: 11/315 - (3%)

  Fly     8 YFKHNDGTHIQGIGLGTFASTE---GDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAE 69
            |.:.:||.||..:|.|||...|   ....:|...|||.|:||||:||||.||.|||.|:|.|:|:
Mouse     6 YMELSDGHHIPVLGFGTFVPGEVSKSMVAKATKIAIDAGFRHIDSAYFYQNEEEVGLAIRSKVAD 70

  Fly    70 GVIKREDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDAN 134
            |.::|||||.|:||.|..|.||.|:....::|:.:.||||||||||.|.|.|  ..|:|||.|.|
Mouse    71 GTVRREDIFYTSKLPCTCHRPELVQPCLEQSLRKLQLDYVDLYLIHCPVSMK--PGNDLIPTDEN 133

  Fly   135 GEVELVDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLL--ANCKIKPIHNQIEVHPALDQ 197
            |::....:|..|||.||||..|.||.|||||||||..||..:|  ...:.||:.||:|.||.|:|
Mouse   134 GKLLFDTVDLCDTWEAMEKCKDSGLAKSIGVSNFNRRQLEMILNKPGLRYKPVCNQVECHPYLNQ 198

  Fly   198 KKLIALCKKNGILVTAFSPLGRHNA----ELRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELG 258
            .||:..||...|::.|:..||....    |...|..:.|..:.|:|:|:.::.|.:.:||:::.|
Mouse   199 SKLLDYCKSKDIVLVAYGALGSQRCKNWIEENAPYLLEDPTLCAMAEKHKQTPALISLRYLLQRG 263

  Fly   259 TIPLPKSSNPKRIEENFNVFDFKLDAEDHAILDSYHNGERVAHARQAIKSKYYPF 313
            .:.:.||.|.|||:||..||:|.|.|||.|::|..:...|.|.||.......|||
Mouse   264 IVIVTKSFNEKRIKENLKVFEFHLPAEDMAVIDRLNRNYRYATARIISAHPNYPF 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	134/299 (45%)
Akr1cl	NP_081858.2	AKR_AKR1C1-35	5..307	CDD:381334	136/302 (45%)