Protein Alignment CG12766 and Akr1a1

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_067448.1
• Gene: Akr1a1 / 58810
• MGIID: 1929955
• Length: 325
• Species: Mus musculus
• Alignment Length: 314
• Identity: 133/314 - (42%)
• Similarity: 191/314 - (60%)
• Gaps: 27/314 - (8%)

  Fly    20 IGLGTFASTEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEG-VIKREDIFITTKL 83
            |||||:.|..|..:.|:.||:..||||||.|..||||.|:|.|:::.:..| .:.||::|:|:||
Mouse    17 IGLGTWKSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKESVGSGKAVPREELFVTSKL 81

  Fly    84 WCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGEVELVDIDYLDTW 148
            |...|.||.||.|.||||.::.|:|:||||:|||:::: ||||. .||:|:|.|......|.:||
Mouse    82 WNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFE-RGDNP-FPKNADGTVRYDSTHYKETW 144

  Fly   149 GAMEKLVDLGLTKSIGVSNFNEEQLTRLLANCKIKPIHNQIEVHPALDQKKLIALCKKNGILVTA 213
            .|:|.||..||.|::|:||||..|:..:|:...::|...|:|.||.|.|.:|||.|...|:.|||
Mouse   145 KALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCHARGLEVTA 209

  Fly   214 FSPLG------RHNAELRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTIPLPKSSNPKRIE 272
            :||||      ||..|   |..:.:..|.|:|:|:.:|.||:::|:.::...|.:|||.||.||.
Mouse   210 YSPLGSSDRAWRHPDE---PVLLEEPVVLALAEKHGRSPAQILLRWQVQRKVICIPKSINPSRIL 271

  Fly   273 ENFNVFDFKLDAEDHAILDSYH------------NGERVAHARQAIKSKYYPFN 314
            :|..||||....|:...||:.:            :|:||  .|.| ....||||
Mouse   272 QNIQVFDFTFSPEEMKQLDALNKNWRYIVPMITVDGKRV--PRDA-GHPLYPFN 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	125/297 (42%)
Akr1a1	NP_067448.1	AKR_AKR1A1-4	8..312	CDD:381332	127/301 (42%)