Protein Alignment CG12766 and Akr1e1

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_061347.2
• Gene: Akr1e1 / 56043
• MGIID: 1914758
• Length: 301
• Species: Mus musculus
• Alignment Length: 302
• Identity: 142/302 - (47%)
• Similarity: 189/302 - (62%)
• Gaps: 7/302 - (2%)

  Fly    16 HIQGIGLGTFASTEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGVIKREDIFIT 80
            :|..:||||:.::.|:...||..||::||||.|.||.|.||:|||..:.:||.|||:||||:|:.
Mouse     3 NIPTVGLGTWKASPGEVTDAVKLAINLGYRHFDCAYLYHNESEVGMGISEKIKEGVVKREDLFVV 67

  Fly    81 TKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGEVELVDIDYL 145
            :||||..|:...|:.||..||:.:.|||:||||||||..:| .|:.: ||.|.||:|......:|
Mouse    68 SKLWCTCHKKSLVKTACTNTLEALNLDYLDLYLIHWPMGFK-PGEKD-IPLDRNGKVIPSHTSFL 130

  Fly   146 DTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLL--ANCKIKPIHNQIEVHPALDQKKLIALCKKNG 208
            |||.|||.||..||.|::||||||.|||.|||  ...:::||.||||.||.|:|||||..|.|..
Mouse   131 DTWEAMEDLVFEGLVKNLGVSNFNHEQLERLLDKPGLRVRPITNQIECHPYLNQKKLIDFCHKRN 195

  Fly   209 ILVTAFSPLGRHNAELRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTIPLPKSSNPKRIEE 273
            :.|||:.|||.......   .|.|..::.||.|:.||.||::||:.|:...|.:|||..|.||.|
Mouse   196 VSVTAYRPLGGSGGGFH---LMDDTVIRKIAKKHGKSPAQILIRFQIQRNLIVIPKSVTPSRIRE 257

  Fly   274 NFNVFDFKLDAEDHAILDSYHNGERVAHARQAIKSKYYPFNV 315
            |..||||:|..:|...|.|.....|:|........:.|||::
Mouse   258 NIQVFDFELTEKDMEELLSLDKNLRLATFPTTENHQDYPFHI 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	137/284 (48%)
Akr1e1	NP_061347.2	AKR_SF	1..301	CDD:444925	142/302 (47%)