Protein Alignment CG12766 and akr1b1.2

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_001070715.1
• Gene: akr1b1.2 / 553452
• ZFINID: ZDB-GENE-041210-132
• Length: 316
• Species: Danio rerio
• Alignment Length: 310
• Identity: 146/310 - (47%)
• Similarity: 196/310 - (63%)
• Gaps: 7/310 - (2%)

  Fly    10 KHNDGTHIQGIGLGTFASTEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGVIKR 74
            |.|.|..:..:||||:.|..|....||..||..||||||.|..|.||.|||..::..|.:||:||
Zfish     6 KLNTGADMPILGLGTWKSPPGKVAEAVKAAIAAGYRHIDGAAVYNNETEVGEGIKAMIKDGVVKR 70

  Fly    75 EDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGEVEL 139
            |::|:.:||||.|||...|:.||:|||.::.|||:||||||||..:|  ..:|..|.|:.|....
Zfish    71 EELFVVSKLWCTFHEKALVKGACQKTLSDLNLDYLDLYLIHWPMGFK--SGSEQFPLDSEGLTIG 133

  Fly   140 VDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLL--ANCKIKPIHNQIEVHPALDQKKLIA 202
            .|..:||||..||:|||.||.|:||:||||.||:..:|  ...|.||.:||:|.||.|.|.|||:
Zfish   134 DDSSFLDTWEGMEELVDAGLVKAIGISNFNREQIEAILNKPGLKYKPANNQVECHPYLTQDKLIS 198

  Fly   203 LCKKNGILVTAFSPLG---RHNAELRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTIPLPK 264
            .|:..||.|||:||||   |..|:...|:.:.|..::|||:|:.|:.|||:||:.|:...|.:||
Zfish   199 YCQSKGITVTAYSPLGSPDRPWAKPEDPSLLDDPNIKAIAEKHKKTTAQVLIRFQIQRNVIVIPK 263

  Fly   265 SSNPKRIEENFNVFDFKLDAEDHAILDSYHNGERVAHARQAIKSKYYPFN 314
            |..|:||:|||.||||:|..||...:.|::...|.......:|.:.||||
Zfish   264 SITPQRIQENFQVFDFELSEEDMKTILSFNRNFRACPMHWGVKHRDYPFN 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	140/293 (48%)
akr1b1.2	NP_001070715.1	AKR_SF	10..316	CDD:444925	144/306 (47%)