Protein Alignment CG12766 and akr1a1

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_001016137.1
• Gene: akr1a1 / 548891
• XenbaseID: XB-GENE-1014353
• Length: 327
• Species: Xenopus tropicalis
• Alignment Length: 327
• Identity: 137/327 - (41%)
• Similarity: 203/327 - (62%)
• Gaps: 16/327 - (4%)

  Fly     1 MTGKVEYYFKHNDGTHIQGIGLGTFASTEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRK 65
            |...|||...:. |..|..|||||:.|..|..:.||.:|:.|||||||.|:.||||.|||.|:::
 Frog     1 MATAVEYETLYT-GQKIPLIGLGTWKSAPGQVKDAVKYALGVGYRHIDCAFVYGNETEVGEAIKE 64

  Fly    66 KI-AEGVIKREDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELI 129
            .: ::..:.||::|:|:|||.|.|.|:.||.|.||||:::.|||:||||:|||:::| ||| ::.
 Frog    65 SVGSDKGLSREEVFVTSKLWNNKHHPDDVECALRKTLQDLQLDYLDLYLMHWPYAFK-RGD-QIF 127

  Fly   130 PKDANGEVELVDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLLANCKIKPIHNQIEVHPA 194
            |::.:|.|:....||.|||.||||||..||||:||:||||:.|:..:::...:||...|:|.||.
 Frog   128 PQNPDGSVQYDLTDYKDTWKAMEKLVKQGLTKAIGLSNFNKRQIDDIISIATVKPAVLQVECHPY 192

  Fly   195 LDQKKLIALCKKNGILVTAFSPLGRHNAELR---TPTFMYDGKVQAIADKYNKSIAQVVIRYVIE 256
            |.|.:|||.|..:|::.|.:||||..:...|   .|..:.:..:.|:|.||.||.||:::|:.::
 Frog   193 LAQNELIAYCHAHGLVFTGYSPLGSPDRSWRKPEDPVLLEEPGIIAMAKKYGKSEAQILLRWQVQ 257

  Fly   257 LGTIPLPKSSNPKRIEENFNVFDFKLDAEDHAILDSYHNGERVAHARQAIKSK---------YYP 312
            ...:.:|||..|.||.:||.||||.|..|:..::.:.:...|.......:..|         .||
 Frog   258 RKVVSIPKSVTPTRILQNFQVFDFSLSEEEMQLIGALNKNWRYIIPLITVNGKSVPRDAGHPLYP 322

  Fly   313 FN 314
            ||
 Frog   323 FN 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	128/295 (43%)
akr1a1	NP_001016137.1	AKR_AKR1A1-4	10..314	CDD:381332	129/306 (42%)