Protein Alignment CG12766 and Akr1c12l1

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_001129216.1
• Gene: Akr1c12l1 / 498790
• RGDID: 1559604
• Length: 323
• Species: Rattus norvegicus
• Alignment Length: 314
• Identity: 130/314 - (41%)
• Similarity: 175/314 - (55%)
• Gaps: 11/314 - (3%)

  Fly    10 KHNDGTHIQGIGLGTFASTE---GDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGV 71
            |.|||..|..:|.||....|   .....||..|||.||.|||||..|..|.|:|.|::.||..||
  Rat     9 KLNDGHFIPALGFGTSIPNEVPKSKSLEAVHLAIDAGYHHIDTASAYQIEEEIGQAIQSKIKAGV 73

  Fly    72 IKREDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGE 136
            :||||:||||||||....||.|:.|..|:|||:.|||.|||::|:|...| .|| :.:|.|..|:
  Rat    74 VKREDMFITTKLWCTCFRPELVKPALEKSLKNLQLDYADLYIMHYPVPMK-SGD-KYLPVDDKGK 136

  Fly   137 VELVDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLL--ANCKIKPIHNQIEVHPALDQKK 199
            ..|..:|:.|||..:||..|.||.|||||||||.:||.|||  ...|.||:.||:|.|..::|.|
  Rat   137 WLLDTVDFCDTWEMLEKCKDAGLVKSIGVSNFNHKQLERLLNKPGLKYKPVCNQVECHLYMNQSK 201

  Fly   200 LIALCKKNGILVTAFSPLGRHN----AELRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTI 260
            |:..||...|::.|:..||...    .:..:|..:.|..:..:|.|..:|.|.:.:||:::...:
  Rat   202 LLDYCKSKDIVLVAYGALGTQRYKEWVDQNSPVLLDDPVLCDVAKKNKRSPALIALRYLVQREVV 266

  Fly   261 PLPKSSNPKRIEENFNVFDFKLDAEDHAILDSYHNGERVAHARQAIKSKYYPFN 314
            ||.:|.....:.||..||:|:|..||...||..:...|...|........|||:
  Rat   267 PLAQSFKENEMRENLQVFEFQLSPEDMKTLDGLNKNFRYLSAEFLAGHPEYPFS 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	125/297 (42%)
Akr1c12l1	NP_001129216.1	AKR_AKR1C1-35	6..308	CDD:381334	126/300 (42%)