Protein Alignment CG12766 and akr1c4

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: XP_031753743.1
• Gene: akr1c4 / 496490
• XenbaseID: XB-GENE-5895888
• Length: 328
• Species: Xenopus tropicalis
• Alignment Length: 314
• Identity: 138/314 - (43%)
• Similarity: 192/314 - (61%)
• Gaps: 19/314 - (6%)

  Fly    12 NDGTHIQGIGLGTFASTE---GDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGVIK 73
            :||..|..:||||:||.|   .|...|...|||:||||||.||.||||.::|.|:|.|||:|.:|
 Frog    20 HDGNAIPVMGLGTYASAEVPKSDGTEATKLAIDLGYRHIDCAYIYGNEVQIGEAIRSKIADGTVK 84

  Fly    74 REDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDA--NGE 136
            ||:||.|.||||:|..|..|......:||.:.|||:||:::|||||.|        |.||  |..
 Frog    85 REEIFYTGKLWCSFFSPNLVRQGLEASLKALQLDYLDLFIMHWPFSVK--------PSDAHSNQP 141

  Fly   137 VELVDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLLA--NCKIKPIHNQIEVHPALDQKK 199
            ::..|:|:..||.|:|...|.||.|||||||||..||.|||:  ..|.||:.||:|.|..|:|.|
 Frog   142 LDFDDVDFCLTWEALEGCKDAGLVKSIGVSNFNRRQLERLLSKPGLKYKPVCNQVEYHVYLNQSK 206

  Fly   200 LIALCKKNGILVTAFSPLG--RHN--AELRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTI 260
            |...||.:.|::.|:|.||  |.|  .:..:|..:.|..::::|.|||:|.|:|.:|::::.|.:
 Frog   207 LHEYCKCHNIVLVAYSVLGTARDNTWVDPNSPVLLEDPVLRSVAAKYNRSPAEVAMRFILQKGAV 271

  Fly   261 PLPKSSNPKRIEENFNVFDFKLDAEDHAILDSYHNGERVAHARQAIKSKYYPFN 314
            .|.||.||.|:::|..||:|:|..||..:||..:...|.|......:...|||:
 Frog   272 VLAKSFNPTRLKQNLGVFEFELKPEDMEMLDGLNRNLRYAQFTVMKQHPEYPFH 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	133/297 (45%)
akr1c4	XP_031753743.1	AKR_SF	15..313	CDD:444925	135/300 (45%)