Protein Alignment CG12766 and akr1c8

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_001004955.1
• Gene: akr1c8 / 448368
• XenbaseID: XB-GENE-5757727
• Length: 324
• Species: Xenopus tropicalis
• Alignment Length: 312
• Identity: 141/312 - (45%)
• Similarity: 186/312 - (59%)
• Gaps: 11/312 - (3%)

  Fly    12 NDGTHIQGIGLGTFAS---TEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGVIK 73
            |||..:..:|.||:|.   .:...|.....||||||||||:|:|||||.|||.|:|.|||:|.:|
 Frog    12 NDGHKMPVLGFGTYAPQKFPKSLAEEGTKVAIDVGYRHIDSAFFYGNEVEVGRAIRAKIADGTVK 76

  Fly    74 REDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGEVE 138
            |||:|.|.|||..||.||||..|..|:|.::.|||:||::||.|...| .||:.| |.|.||:..
 Frog    77 REDVFYTGKLWSTFHTPERVRPALEKSLNDLQLDYMDLFIIHIPVELK-PGDDPL-PLDENGKFI 139

  Fly   139 LVDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLL--ANCKIKPIHNQIEVHPALDQKKLI 201
            ..:.|..|||.|:||..|.||.:||||||||.:||..:|  ...|.||:.||:|.|..|:|.||:
 Frog   140 YHNTDIRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPGLKYKPVCNQVECHVYLNQSKLL 204

  Fly   202 ALCKKNGILVTAFSPLGRHNAEL----RTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTIPL 262
            ..||...|::.||..||....|.    ..|..:.|..:.|||.|:|.:.|||.:||:::.|.:.|
 Frog   205 EFCKSKDIVLVAFGVLGSSRDESWIDPNLPVLLEDPVLNAIAKKHNCTPAQVAMRYLLQRGVVVL 269

  Fly   263 PKSSNPKRIEENFNVFDFKLDAEDHAILDSYHNGERVAHARQAIKSKYYPFN 314
            .||..|.||::||.||:..|||||...:|..:...|..:|........|||:
 Frog   270 VKSFTPARIQQNFQVFNVHLDAEDMRNVDGINRNLRYDYAPMWSDHPKYPFH 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	136/295 (46%)
akr1c8	NP_001004955.1	AKR_AKR1C1-35	8..306	CDD:381334	136/295 (46%)