Protein Alignment CG12766 and AKR1B15

DIOPT Version :9

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_001074007.2
• Gene: AKR1B15 / 441282
• HGNCID: 37281
• Length: 344
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 135/294 - (45%)
• Similarity: 180/294 - (61%)
• Gaps: 7/294 - (2%)

  Fly    26 ASTEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGVIKREDIFITTKLWCNFHEP 90
            ||..|..:.||..|||..|||||.||||.|:.|||.|:::||.|..:.|||:||.:|:|..|.|.
Human    50 ASLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQEKIQEKAVMREDLFIVSKVWPTFFER 114

  Fly    91 ERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGEVELVDIDYLDTWGAMEKLV 155
            ..|..|..||||::.|.|:|:||||||..:| .|| :..|||..|.:......:||.|.|||:||
Human   115 PLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK-TGD-DFFPKDDKGNMISGKGTFLDAWEAMEELV 177

  Fly   156 DLGLTKSIGVSNFNEEQLTRLL--ANCKIKPIHNQIEVHPALDQKKLIALCKKNGILVTAFSPLG 218
            |.||.|::||||||..|:.|||  ...|.||:.||:|.||.|.|:|||..|...||.|||:||||
Human   178 DEGLVKALGVSNFNHFQIERLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLG 242

  Fly   219 ---RHNAELRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTIPLPKSSNPKRIEENFNVFDF 280
               |..|:...|:.:.|.|::.||.|:.|:.|||:||:.|:.....:|||..|..|.||..||||
Human   243 SPDRPWAKPEDPSLLEDPKIKEIAAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDF 307

  Fly   281 KLDAEDHAILDSYHNGERVAHARQAIKSKYYPFN 314
            ||..|:.|.:.|::...|....::....:.:||:
Human   308 KLSDEEMATILSFNRNWRAFDFKEFSHLEDFPFD 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	ARA1	5..298	CDD:223729	132/276 (48%)
		Tas	12..299	CDD:223739	132/277 (48%)
AKR1B15	NP_001074007.2	ARA1	56..325	CDD:223729	129/270 (48%)
		Tas	57..317	CDD:223739	128/261 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158436
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.760