Protein Alignment CG12766 and akr1b1.1

DIOPT Version :10

• Sequence 1: NP_647839.1
• Gene: CG12766 / 38462
• FlyBaseID: FBgn0035476
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_001002048.1
• Gene: akr1b1.1 / 415138
• ZFINID: ZDB-GENE-040625-7
• Length: 315
• Species: Danio rerio
• Alignment Length: 308
• Identity: 145/308 - (47%)
• Similarity: 195/308 - (63%)
• Gaps: 7/308 - (2%)

  Fly    12 NDGTHIQGIGLGTFASTEGDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGVIKRED 76
            |:|..:..:||||:.|..|:...||..||..||||||.|:.|.||.|||..:...|.:||:||||
Zfish     7 NNGAKMPIVGLGTWRSPPGEVTEAVKSAILSGYRHIDGAHVYENENEVGDGICAMINQGVVKRED 71

  Fly    77 IFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGEVELVD 141
            :||.:||||.|||...|..||.|||.::.||||||||:|:|...|  ...:|.|.|.:|.|...:
Zfish    72 LFIVSKLWCTFHEKHLVRGACEKTLSDLKLDYVDLYLMHFPMGTK--PGKDLFPLDKDGHVIPDN 134

  Fly   142 IDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLL--ANCKIKPIHNQIEVHPALDQKKLIALC 204
            .::|:||.|||:|||.||.|:||:||||.:|:..:|  ...|.||.:||||.||.|.|:|||..|
Zfish   135 SNFLETWEAMEELVDAGLVKAIGISNFNRDQIEAILNKPGLKYKPANNQIECHPYLTQEKLINYC 199

  Fly   205 KKNGILVTAFSPLGRHN---AELRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTIPLPKSS 266
            :..||.|||:||||..|   |:...|:.:.|.|::|||||:.|:.|||:|.:.|:...:.:|||.
Zfish   200 QSKGITVTAYSPLGSPNRPWAQADEPSLLEDPKIKAIADKHGKTTAQVLIHFHIQRNVVVIPKSV 264

  Fly   267 NPKRIEENFNVFDFKLDAEDHAILDSYHNGERVAHARQAIKSKYYPFN 314
            .|.||:|||.||||:|..|:...:.|::...|......|.|.|.:|.|
Zfish   265 TPSRIKENFEVFDFELSKEEMNTILSFNRNFRAFGLEWASKHKDFPLN 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	AKR_AKR2E1-5	7..299	CDD:381342	139/291 (48%)
akr1b1.1	NP_001002048.1	AKR_AKR1B1-19	9..315	CDD:381333	144/306 (47%)