DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12766 and Akr1c1

DIOPT Version :9

Sequence 1:	NP_647839.1	Gene:	CG12766 / 38462	FlyBaseID:	FBgn0035476	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_001028869.1	Gene:	Akr1c1 / 307092	RGDID:	1306847	Length:	323	Species:	Rattus norvegicus

Alignment Length:	302	Identity:	136/302 - (45%)
Similarity:	184/302 - (60%)	Gaps:	17/302 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 NDGTHIQGIGLGTFASTE---GDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGVIK 73
            :||..|..:|.||:|..|   .....|...|||.|:||||:|..|.||.|||.|:|.|||:|.:|
  Rat    11 SDGHFIPVLGFGTYAPREVPKSKALEATKIAIDAGFRHIDSAAVYQNEKEVGLAIRSKIADGTVK 75

  Fly    74 REDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYRGDNELIPKDANGEVE 138
            |||||.|:|:||.|:.||||:....::||.:.|:||||||||:|.:.|  .:.:|..||.|.::.
  Rat    76 REDIFYTSKVWCTFNHPERVQVCLEQSLKQLQLEYVDLYLIHFPMALK--PEEDLKAKDENEKLL 138

  Fly   139 LVDIDYLDTWGAMEKLVDLGLTKSIGVSNFNEEQLTRLL--ANCKIKPIHNQIEVHPALDQKKLI 201
            ...:|..|||.||||..|.||.|||||||||..||.::|  ...|.:|:.||:|.||.|:|:||:
  Rat   139 FDVVDICDTWKAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKHRPVCNQVECHPYLNQRKLL 203

  Fly   202 ALCKKNGILVTAFSPLGRHN----AELRTPTFMYDGKVQAIADKYNKSIAQVVIRYVIELGTIPL 262
            ..||...|::.|:|.||.|.    .:...|..:.|..:.|||.|||.:.|.:.:||.:|.|.:.|
  Rat   204 DFCKSKDIVLVAYSALGSHRETRCVDKSLPVLLADPVLCAIAKKYNWTPALIALRYQLERGVVVL 268

  Fly   263 PKSSNPKRIEENFNVFDFKLDAEDHAILDS------YHNGER 298
            .||...|||:||..||:|:|.:||..:||.      |.:|.|
  Rat   269 AKSFTEKRIKENMQVFEFQLTSEDMKVLDGLNKNIRYMSGSR 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12766	NP_647839.1	ARA1	5..298	CDD:223729	135/300 (45%)
CG12766	NP_647839.1	Tas	12..299	CDD:223739	136/302 (45%)
Akr1c1	NP_001028869.1	ARA1	5..305	CDD:223729	133/295 (45%)
Akr1c1	NP_001028869.1	Tas	16..297	CDD:223739	129/282 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	1	1.000	-	-		mtm8954
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.730